Article · Wikipedia archive · Last revised Jun 11, 2026

Proscillaridin

Proscillaridin is a cardiac glycoside, a type of compound with strong and usually toxic effects on heart muscle, with occasional medical applications - although Proscillaridin has no known medical applications. It is of the bufanolide type and can be obtained from plants of the genus Scilla and in Drimia maritima.

Last revised
Jun 11, 2026
Read time
≈ 1 min
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Citations
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Source
Wikipedia ↗
Proscillaridin
Clinical data
Other names14β-Hydroxy-3β-[α-L-rhamnopyranosyl)oxy]bufa-4,20,22-trienolide
AHFS/Drugs.comInternational Drug Names
ATC code
Identifiers
  • 5-[(3S,8R,9S,10R,13R,14S,17R)-14-Hydroxy- 10,13-dimethyl-3-((2R,3R,4R,5R,6R)-3,4,5-trihydroxy- 6-methyltetrahydro-2H-pyran-2-yloxy)-2,3,6,7,8,9,10,11,12,13,14,15,16,17-tetradecahydro- 1H-cyclopenta[a]phenanthren-17-yl]-2H-pyran-2-one
CAS Number
PubChem CID
ChemSpider
UNII
ChEMBL
CompTox Dashboard (EPA)
ECHA InfoCard100.006.702
Chemical and physical data
FormulaC30H42O8
Molar mass530.658 g·mol−1
3D model (JSmol)
  • O=C1OC=C([C@H]2CC[C@]3([C@@]2(CC[C@H]4[C@H]3CCC5=C[C@H](CC[C@@]54C)O[C@@H]6O[C@@H](C)[C@@H]([C@H]([C@H]6O)O)O)C)O)C=C1
  • InChI=1S/C30H42O8/c1-16-24(32)25(33)26(34)27(37-16)38-19-8-11-28(2)18(14-19)5-6-22-21(28)9-12-29(3)20(10-13-30(22,29)35)17-4-7-23(31)36-15-17/h4,7,14-16,19-22,24-27,32-35H,5-6,8-13H2,1-3H3/t16-,19-,20+,21-,22+,24-,25+,26+,27-,28-,29+,30-/m0/s1 checkY
  • Key:MYEJFUXQJGHEQK-ALRJYLEOSA-N checkY
 ☒NcheckY (what is this?)  (verify)

Proscillaridin is a cardiac glycoside, a type of compound with strong and usually toxic effects on heart muscle, with occasional medical applications - although Proscillaridin has no known medical applications. It is of the bufanolide type and can be obtained from plants of the genus Scilla and in Drimia maritima (Scilla maritima).1

The aglycone of proscillaridin is scillarenin.

References

References

  1. Kedra M, Kedrowa S (May 1968). "[Clinical evaluation of Proscillaridin A, a glycoside of Scilla maritima]". Polski Tygodnik Lekarski. 23 (19): 714–6. PMID 4876207.