Article · Wikipedia archive · Last revised Jul 30, 2026

Juno (psychedelic)

Juno, also known as 4,6-dimethyl-2,5-dimethoxyamphetamine or as 6-methyl-DOM, is a possible psychedelic drug of the phenethylamine, amphetamine, and DOx families related to DOM. It is the 6-methyl derivative of DOM and a positional isomer of Ganesha (3-methyl-DOM). The drug is one of Alexander Shulgin's "ten classic ladies", a series of methylated DOM derivatives. DOM, Ganesha, and DOTMA are all known to be active psychedelics, so Juno is expected to be an active psychedelic as well, but has not yet been tested. Juno was first described by Shulgin in his 1991 book PiHKAL. He shared in PiHKAL that he had had Juno on a shelf in his lab for almost 14 years but had never gotten around to trying it. It is a controlled substance in Canada under phenethylamine blanket-ban language. The drug is not an explicitly controlled substance in the United States, but may be considered scheduled as an isomer of DOET.

Last revised
Jul 30, 2026
Read time
≈ 2 min
Length
446 w
Citations
19
Source
Juno
Clinical data
Other namesJUNO; 3,6-Dimethoxy-2,4-dimethylamphetamine; 4,6-Dimethyl-2,5-dimethoxyamphetamine; 6-Methyl-DOM; 6-Me-DOM
Routes of
administration
Unknown12
Drug classSerotonergic psychedelic; Hallucinogen
ATC code
  • None
Pharmacokinetic data
Duration of actionUnknown12
Identifiers
  • 1-(3,6-dimethoxy-2,4-dimethylphenyl)propan-2-amine
Chemical and physical data
FormulaC13H21NO2
Molar mass223.316 g·mol−1
3D model (JSmol)
  • COc1c(C)cc(c(c1C)CC(N)C)OC
  • InChI=1S/C13H21NO2/c1-8-6-12(15-4)11(7-9(2)14)10(3)13(8)16-5/h6,9H,7,14H2,1-5H3
  • Key:GNNNCQKNVSPUBX-UHFFFAOYSA-N

Juno, also known as 4,6-dimethyl-2,5-dimethoxyamphetamine or as 6-methyl-DOM, is a possible psychedelic drug of the phenethylamine, amphetamine, and DOx families related to DOM.123 It is the 6-methyl derivative of DOM and a positional isomer of Ganesha (3-methyl-DOM).123 The drug is one of Alexander Shulgin's "ten classic ladies", a series of methylated DOM derivatives.13 DOM, Ganesha, and DOTMA (Julia; 3,6-dimethyl-DOM) are all known to be active psychedelics, so Juno is expected to be an active psychedelic as well, but has not yet been tested.12 Juno was first described by Shulgin in his 1991 book PiHKAL (Phenethylamines I Have Known and Loved).1 He shared in PiHKAL that he had had Juno on a shelf in his lab for almost 14 years but had never gotten around to trying it.1 It is a controlled substance in Canada under phenethylamine blanket-ban language.4 The drug is not an explicitly controlled substance in the United States, but may be considered scheduled as an isomer of DOET.56

See also

See also

References

References

  1. Shulgin A, Shulgin A (September 1991). PiHKAL: A Chemical Love Story. Berkeley, California: Transform Press. ISBN 0-9630096-0-5. OCLC 25627628. "And there is the 6-hydrogen atom [of DOM] which can become a 6-methyl group to produce a compound called JUNO, who is pretty much a lady’s lady, or should I say a woman’s woman." [...] "And, finally, JUNO (3,6-dimethoxy-2,4-dimethylamphetamine) has been made (from 2,5-dimethoxy-m-xylene, which was reacted with POCl3 and N-methylformanilide to the benzaldehyde, mp 53–54 °C, and to the nitrostyrene with nitroethane, mp 73–74 °C from cyclohexane, and to the final amine hydrochloride with LAH in THF). Rather amazingly, I have had JUNO on the shelf for almost 14 years and have not yet gotten around to tasting it."
  2. Trachsel D, Lehmann D, Enzensperger C (2013). Phenethylamine: von der Struktur zur Funktion [Phenethylamines: From Structure to Function]. Nachtschatten-Science (in German) (1 ed.). Solothurn: Nachtschatten-Verlag. ISBN 978-3-03788-700-4. OCLC 858805226. Archived from the original on 21 August 2025.
  3. Ger A, Ger D (April 2011). "Triple Goddess of the Night". British Neuroscience Association Bulletin. 63: 28–30.
  4. "Controlled Drugs and Substances Act". Department of Justice Canada. Retrieved 19 January 2026.
  5. Orange Book: List of Controlled Substances and Regulated Chemicals (January 2026) (PDF), United States: U.S. Department of Justice: Drug Enforcement Administration (DEA): Diversion Control Division, January 2026
  6. Drug Enforcement Administration (3 December 2007). "Definition of "Positional Isomer" as It Pertains to the Control of Schedule I Controlled Substances". Federal Register.
External links