ZBED6

ZBED6
Identifiers
Aliases	ZBED6, MGR, zinc finger BED-type containing 6
External IDs	OMIM: 613512; MGI: 3828086; HomoloGene: 130066; GeneCards: ZBED6; OMA:ZBED6 - orthologs
Gene location (Human)
Chr.	Chromosome 1 (human)
End	203,854,999 bp
Gene location (Mouse)
Chr.	Chromosome 1 (mouse)
End	133,589,056 bp
RNA expression pattern
	Top expressed in
	bone marrow cell; ; gonad; ; epithelium of colon; ; tonsil; ; islet of Langerhans; ; stromal cell of endometrium; ; Achilles tendon; ; duodenum; ; smooth muscle tissue; ; sural nerve;
	Top expressed in
	ascending aorta; ; aortic valve; ; tail of embryo; ; olfactory tubercle; ; genital tubercle; ; arcuate nucleus; ; median eminence; ; medial geniculate nucleus; ; inferior colliculi; ; paraventricular nucleus of hypothalamus;
	More reference expression data
	n/a
Gene ontology
Molecular function	DNA binding; protein dimerization activity; metal ion binding; DNA-binding transcription factor activity; RNA polymerase II transcription regulatory region sequence-specific DNA binding; DNA-binding transcription factor activity, RNA polymerase II-specific;
Cellular component	nucleolus; nucleus;
Biological process	negative regulation of transcription, DNA-templated; regulation of transcription, DNA-templated; transcription, DNA-templated; regulation of transcription by RNA polymerase II;
	Sources:Amigo / QuickGO
Orthologs
	100381270
	667118
	ENSG00000257315
	ENSMUSG00000094410
	P86452
	D2EAC2
	NM_001174108; NM_001395895
	NM_001166552; NM_001395904
	NP_001167579
	NP_001160024; NP_001382833
	Wikidata
View/Edit Human	View/Edit Mouse

Zinc finger, BED-type containing 6 is a protein that in humans is encoded by the ZBED6 gene.⁵

References

GRCh38: Ensembl release 89: ENSG00000257315 – Ensembl, May 2017
GRCm38: Ensembl release 89: ENSMUSG00000094410 – Ensembl, May 2017
"Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
"Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
"Entrez Gene: Zinc finger, BED-type containing 6". Retrieved 2012-03-15.

Further reading

Markljung E, Jiang L, Jaffe JD, Mikkelsen TS, Wallerman O, Larhammar M, Zhang X, Wang L, Saenz-Vash V, Gnirke A, Lindroth AM, Barrés R, Yan J, Strömberg S, De S, Pontén F, Lander ES, Carr SA, Zierath JR, Kullander K, Wadelius C, Lindblad-Toh K, Andersson G, Hjälm G, Andersson L (Dec 2009). O'Rahilly S (ed.). "ZBED6, a novel transcription factor derived from a domesticated DNA transposon regulates IGF2 expression and muscle growth". PLOS Biology. 7 (12) e1000256. doi:10.1371/journal.pbio.1000256. PMC 2780926. PMID 20016685.
Butter F, Kappei D, Buchholz F, Vermeulen M, Mann M (Apr 2010). "A domesticated transposon mediates the effects of a single-nucleotide polymorphism responsible for enhanced muscle growth". EMBO Reports. 11 (4): 305–11. doi:10.1038/embor.2010.6. PMC 2854606. PMID 20134481.
Andersson L (2010). "Studying phenotypic evolution in domestic animals: a walk in the footsteps of Charles Darwin". Cold Spring Harbor Symposia on Quantitative Biology. 74: 319–25. doi:10.1101/sqb.2009.74.039. PMID 20375320.

[refGRCh38Ensembl-1] GRCh38: Ensembl release 89: ENSG00000257315 – Ensembl, May 2017

[refGRCm38Ensembl-2] GRCm38: Ensembl release 89: ENSMUSG00000094410 – Ensembl, May 2017

[3] "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[4] "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[entrez-5] "Entrez Gene: Zinc finger, BED-type containing 6". Retrieved 2012-03-15.

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