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L-tryptophan—pyruvate aminotransferase

L-tryptophan—pyruvate aminotransferase is an enzyme with systematic name L-tryptophan:pyruvate aminotransferase. This enzyme catalyses the following chemical reaction

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L-tryptophan---pyruvate aminotransferase
Identifiers
EC no.2.6.1.99
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L-tryptophan—pyruvate aminotransferase (EC 2.6.1.99, TAA1 (gene), vt2 (gene)) is an enzyme with systematic name L-tryptophan:pyruvate aminotransferase.123 This enzyme catalyses the following chemical reaction

2D representation of the chemical structure of tryptophan .
tryptophan
+
 
2D representation of the chemical structure of pyruvic acid.
pyruvic acid
 
 
 
Rightward reaction arrow
 
 
 
2D representation of the chemical structure of Q23905803.
indole-3-pyruvic acid
+
 
2D representation of the chemical structure of alanine.
alanine


This plant aminotransferase enzyme, along with indole-3-pyruvate monooxygenase, is responsible for the biosynthesis of the auxin plant hormone indoleacetic acid from L-tryptophan.4

References

References

  1. Tao Y, Ferrer JL, Ljung K, Pojer F, Hong F, Long JA, Li L, Moreno JE, Bowman ME, Ivans LJ, Cheng Y, Lim J, Zhao Y, Ballaré CL, Sandberg G, Noel JP, Chory J (April 2008). "Rapid synthesis of auxin via a new tryptophan-dependent pathway is required for shade avoidance in plants". Cell. 133 (1): 164–76. doi:10.1016/j.cell.2008.01.049. PMC 2442466. PMID 18394996.
  2. Mashiguchi, K.; Tanaka, K.; Sakai, T.; Sugawara, S.; Kawaide, H.; Natsume, M.; Hanada, A.; Yaeno, T.; Shirasu, K.; Yao, H.; McSteen, P.; Zhao, Y.; Hayashi, K.-i.; Kamiya, Y.; Kasahara, H. (8 November 2011). "The main auxin biosynthesis pathway in Arabidopsis". Proceedings of the National Academy of Sciences. 108 (45): 18512–18517. Bibcode:2011PNAS..10818512M. doi:10.1073/pnas.1108434108. PMC 3215075. PMID 22025724.
  3. Phillips KA, Skirpan AL, Liu X, Christensen A, Slewinski TL, Hudson C, Barazesh S, Cohen JD, Malcomber S, McSteen P (February 2011). "vanishing tassel2 encodes a grass-specific tryptophan aminotransferase required for vegetative and reproductive development in maize". The Plant Cell. 23 (2): 550–66. Bibcode:2011PlanC..23..550P. doi:10.1105/tpc.110.075267. PMC 3077783. PMID 21335375.
  4. Zhao Y (March 2012). "Auxin biosynthesis: a simple two-step pathway converts tryptophan to indole-3-acetic acid in plants". Molecular Plant. 5 (2): 334–8. doi:10.1093/mp/ssr104. PMC 3309920. PMID 22155950.
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