Article · Wikipedia archive · Last revised Jul 4, 2026

Trional

Trional (Methylsulfonal) is a sedative-hypnotic and anesthetic drug with GABAergic actions. It has similar effects to Sulfonal, except it is faster acting.

Last revised
Jul 4, 2026
Read time
≈ 1 min
Length
184 w
Citations
3
Source
Wikipedia ↗
Trional
Clinical data
ATC code
  • none
Legal status
Legal status
Identifiers
  • 2,2-bis(ethylsulfonyl)butane
CAS Number
PubChem CID
ChemSpider
UNII
CompTox Dashboard (EPA)
ECHA InfoCard100.000.858
Chemical and physical data
FormulaC8H18O4S2
Molar mass242.35 g·mol−1
3D model (JSmol)
  • CCC(C)(S(=O)(=O)CC)S(=O)(=O)CC
  • InChI=1S/C8H18O4S2/c1-5-8(4,13(9,10)6-2)14(11,12)7-3/h5-7H2,1-4H3 checkY
  • Key:LKACJLUUJRMGFK-UHFFFAOYSA-N checkY
 ☒NcheckY (what is this?)  (verify)

Trional (Methylsulfonal) is a sedative-hypnotic1 and anesthetic drug with GABAergic actions. It has similar effects to Sulfonal, except it is faster acting.2

History

Trional was prepared and introduced by Eugen Baumann and Alfred Kast in 1888.3

Cultural references

Appeared in Agatha Christie's Murder on the Orient Express, And Then There Were None, and other novels such as John Bude's The Lake District Murder as a sleep-inducing sedative; and in In Search of Lost Time (Sodom and Gomorrah) by Marcel Proust as a hypnotic. Sax Rohmer also references trional in his novel Dope.

See also

See also

References

References

  1. "Trional". Merck's 1907 Index. New York: Merck & Co. 1907. p. 448.
  2. Sajous CE (1896). "General Therapeutics". Annual of the Universal Medical Sciences. 5. Philadelphia: F. A. Davis: A-156.
  3. Drinkwater H (1924). Fifty years of medical progress, 1873-1922. New York: The Macmillan Company. p. 40.