Article · Wikipedia archive · Last revised Jul 2, 2026

SRGAP3

SLIT-ROBO Rho GTPase-activating protein 3 is an enzyme that in humans is encoded by the SRGAP3 gene.

Last revised
Jul 2, 2026
Read time
≈ 3 min
Length
632 w
Citations
10
Source
SRGAP3
Available structures
PDBOrtholog search: PDBe RCSB
Identifiers
AliasesSRGAP3, ARHGAP14, MEGAP, SRGAP2, WRP, SLIT-ROBO Rho GTPase activating protein 3
External IDsOMIM: 606525; MGI: 2152938; HomoloGene: 56686; GeneCards: SRGAP3; OMA:SRGAP3 - orthologs
Orthologs
SpeciesHumanMouse
Entrez
Ensembl
UniProt
RefSeq (mRNA)

NM_001033116
NM_001033117
NM_014850

NM_080448
NM_153070

RefSeq (protein)

NP_001028289
NP_055665

NP_536696

Location (UCSC)Chr 3: 8.98 – 9.36 MbChr 6: 112.69 – 112.92 Mb
PubMed search34
Wikidata
View/Edit HumanView/Edit Mouse

SLIT-ROBO Rho GTPase-activating protein 3 is an enzyme that in humans is encoded by the SRGAP3 gene.56


References

References

  1. GRCh38: Ensembl release 89: ENSG00000196220Ensembl, May 2017
  2. GRCm38: Ensembl release 89: ENSMUSG00000030257Ensembl, May 2017
  3. "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  4. "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  5. Endris V, Wogatzky B, Leimer U, Bartsch D, Zatyka M, Latif F, Maher ER, Tariverdian G, Kirsch S, Karch D, Rappold GA (Sep 2002). "The novel Rho-GTPase activating gene MEGAP/ srGAP3 has a putative role in severe mental retardation". Proc Natl Acad Sci U S A. 99 (18): 11754–9. Bibcode:2002PNAS...9911754E. doi:10.1073/pnas.162241099. PMC 129341. PMID 12195014.
  6. "Entrez Gene: SRGAP3 SLIT-ROBO Rho GTPase activating protein 3".
Further reading

Further reading