SPATA5

SPATA5
Identifiers
Aliases	SPATA5, AFG2, SPAF, EHLMRS, spermatogenesis associated 5, NEDHSB
External IDs	OMIM: 613940; MGI: 1927170; HomoloGene: 56920; GeneCards: SPATA5; OMA:SPATA5 - orthologs
Gene location (Human)
Chr.	Chromosome 4 (human)
End	123,319,433 bp
Gene location (Mouse)
Chr.	Chromosome 3 (mouse)
End	37,633,245 bp
RNA expression pattern
	Top expressed in
	tendon of biceps brachii; ; Achilles tendon; ; palpebral conjunctiva; ; gonad; ; testicle; ; bone marrow cell; ; ventricular zone; ; internal globus pallidus; ; sural nerve; ; epithelium of colon;
	Top expressed in
	spermatocyte; ; primitive streak; ; seminiferous tubule; ; primary oocyte; ; spermatid; ; Gonadal ridge; ; genital tubercle; ; tail of embryo; ; epiblast; ; motor neuron;
	More reference expression data
	; ; ; ;
	More reference expression data
Gene ontology
Molecular function	nucleotide binding; ATP binding; ATPase activity; hydrolase activity;
Cellular component	cytoplasm; mitochondrion;
Biological process	multicellular organism development; cell differentiation; brain development; spermatogenesis;
	Sources:Amigo / QuickGO
Orthologs
	166378
	57815
	ENSG00000145375
	ENSMUSG00000027722
	Q8NB90
	Q3UMC0
	NM_145207; NM_001317799; NM_001345856
	NM_001163511; NM_021343; NM_001310473
	NP_001304728; NP_001332785; NP_660208
	NP_001156983; NP_001297402; NP_067318
	Wikidata
View/Edit Human	View/Edit Mouse

Spermatogenesis-associated protein 5 is a protein that in humans is encoded by the SPATA5 gene.⁵⁶

References

GRCh38: Ensembl release 89: ENSG00000145375 – Ensembl, May 2017
GRCm38: Ensembl release 89: ENSMUSG00000027722 – Ensembl, May 2017
"Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
"Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
Katoh Y, Katoh M (Feb 2006). "FGF signaling inhibitor, SPRY4, is evolutionarily conserved target of WNT signaling pathway in progenitor cells". International Journal of Molecular Medicine. 17 (3): 529–32. doi:10.3892/ijmm.17.3.529. PMID 16465403.
"Entrez Gene: SPATA5 spermatogenesis associated 5".

Further reading

Liu Y, Black J, Kisiel N, Kulesz-Martin MF (2000). "SPAF, a new AAA-protein specific to early spermatogenesis and malignant conversion". Oncogene. 19 (12): 1579–88. doi:10.1038/sj.onc.1203442. PMID 10734318.
Hartley JL, Temple GF, Brasch MA (2001). "DNA cloning using in vitro site-specific recombination". Genome Research. 10 (11): 1788–95. doi:10.1101/gr.143000. PMC 310948. PMID 11076863.
Wiemann S, Weil B, Wellenreuther R, et al. (2001). "Toward a catalog of human genes and proteins: sequencing and analysis of 500 novel complete protein coding human cDNAs". Genome Research. 11 (3): 422–35. doi:10.1101/gr.GR1547R. PMC 311072. PMID 11230166.
Simpson JC, Wellenreuther R, Poustka A, et al. (2001). "Systematic subcellular localization of novel proteins identified by large-scale cDNA sequencing". EMBO Reports. 1 (3): 287–92. doi:10.1093/embo-reports/kvd058. PMC 1083732. PMID 11256614.
Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proceedings of the National Academy of Sciences of the United States of America. 99 (26): 16899–903. Bibcode:2002PNAS...9916899M. doi:10.1073/pnas.242603899. PMC 139241. PMID 12477932.
Ota T, Suzuki Y, Nishikawa T, et al. (2004). "Complete sequencing and characterization of 21,243 full-length human cDNAs". Nature Genetics. 36 (1): 40–5. doi:10.1038/ng1285. PMID 14702039.
Wiemann S, Arlt D, Huber W, et al. (2004). "From ORFeome to biology: a functional genomics pipeline". Genome Research. 14 (10B): 2136–44. doi:10.1101/gr.2576704. PMC 528930. PMID 15489336.
Kimura K, Wakamatsu A, Suzuki Y, et al. (2006). "Diversification of transcriptional modulation: large-scale identification and characterization of putative alternative promoters of human genes". Genome Research. 16 (1): 55–65. doi:10.1101/gr.4039406. PMC 1356129. PMID 16344560.
Mehrle A, Rosenfelder H, Schupp I, et al. (2006). "The LIFEdb database in 2006". Nucleic Acids Research. 34 (Database issue): D415–8. doi:10.1093/nar/gkj139. PMC 1347501. PMID 16381901.

[refGRCh38Ensembl-1] GRCh38: Ensembl release 89: ENSG00000145375 – Ensembl, May 2017

[refGRCm38Ensembl-2] GRCm38: Ensembl release 89: ENSMUSG00000027722 – Ensembl, May 2017

[3] "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[4] "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[pmid16465403-5] Katoh Y, Katoh M (Feb 2006). "FGF signaling inhibitor, SPRY4, is evolutionarily conserved target of WNT signaling pathway in progenitor cells". International Journal of Molecular Medicine. 17 (3): 529–32. doi:10.3892/ijmm.17.3.529. PMID 16465403.

[entrez-6] "Entrez Gene: SPATA5 spermatogenesis associated 5".

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