Article · Wikipedia archive · Last revised Jun 26, 2026

Sinecatechins

Sinecatechins is a specific water extract of green tea leaves from Camellia sinensis that is the active ingredient in an ointment approved by the FDA in 2006 as a botanical drug to treat genital warts. Sinecatechins are mostly catechins, 55% of which is epigallocatechin gallate. It was the first botanical drug approved by the US FDA.

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A botanical drawing showing a plant with green leaves and white flowers
Sinecatechins is an extract from the leaves of Camellia sinensis. source ↗

Sinecatechins (USAN, trade names Veregen and Polyphenon E) is a specific water extract of green tea leaves from Camellia sinensis that is the active ingredient in an ointment approved by the FDA in 2006 as a botanical drug to treat genital warts.123 Sinecatechins are mostly catechins, 55% of which is epigallocatechin gallate.4 It was the first botanical drug approved by the US FDA.2

References

References

  1. "Veregen label information" (PDF). Archived from the original (PDF) on February 1, 2016. Retrieved 2015-05-02.
  2. Masters KP (2009). "New Drug Reviews: Sinecatechins (Veregen) for External Genital and Perianal Warts". Am Fam Physician. 80 (12): 1447–1454.
  3. Fürst R, Zündorf I (2014). "Plant-derived anti-inflammatory compounds: hopes and disappointments regarding the translation of preclinical knowledge into clinical progress". Mediators Inflamm. 2014 146832. doi:10.1155/2014/146832. PMC 4060065. PMID 24987194.
  4. Mayeaux EJ, Dunton C (July 2008). "Modern management of external genital warts". J Low Genit Tract Dis. 12 (3): 185–192. doi:10.1097/LGT.0b013e31815dd4b4. PMID 18596459. S2CID 33302840.