SF3B5

SF3B5
Identifiers
Aliases	SF3B5, SF3b10, Ysf3, splicing factor 3b subunit 5
External IDs	OMIM: 617847; MGI: 1913375; HomoloGene: 41825; GeneCards: SF3B5; OMA:SF3B5 - orthologs
Gene location (Human)
Chr.	Chromosome 6 (human)
End	144,095,573 bp
Gene location (Mouse)
Chr.	Chromosome 10 (mouse)
End	12,884,927 bp
RNA expression pattern
	Top expressed in
	anterior pituitary; ; mucosa of transverse colon; ; granulocyte; ; right adrenal gland; ; left adrenal cortex; ; right adrenal cortex; ; olfactory zone of nasal mucosa; ; body of pancreas; ; skin of leg; ; skin of abdomen;
	Top expressed in
	internal carotid artery; ; endocardial cushion; ; efferent ductule; ; abdominal wall; ; mandibular prominence; ; external carotid artery; ; maxillary prominence; ; renal corpuscle; ; endothelial cell of lymphatic vessel; ; migratory enteric neural crest cell;
	More reference expression data
	More reference expression data
Gene ontology
Molecular function	RNA binding;
Cellular component	U12-type spliceosomal complex; spliceosomal complex; precatalytic spliceosome; nucleus; U2 snRNP; nucleoplasm; U2-type precatalytic spliceosome;
Biological process	mRNA processing; RNA splicing; mRNA splicing, via spliceosome;
	Sources:Amigo / QuickGO
Orthologs
	83443
	66125
	ENSG00000169976
	ENSMUSG00000078348
	Q9BWJ5
	Q923D4
	NM_031287
	NM_175102
	NP_112577
	NP_780311
	Wikidata
View/Edit Human	View/Edit Mouse

Splicing factor 3B subunit 5 is a protein that in humans is encoded by the SF3B5 gene.⁵⁶

The protein is a part of splicing factor 3b.

References

GRCh38: Ensembl release 89: ENSG00000169976 – Ensembl, May 2017
GRCm38: Ensembl release 89: ENSMUSG00000078348 – Ensembl, May 2017
"Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
"Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
Will CL, Urlaub H, Achsel T, Gentzel M, Wilm M, Luhrmann R (Sep 2002). "Characterization of novel SF3b and 17S U2 snRNP proteins, including a human Prp5p homologue and an SF3b DEAD-box protein". EMBO J. 21 (18): 4978–88. doi:10.1093/emboj/cdf480. PMC 126279. PMID 12234937.
"Entrez Gene: SF3B5 splicing factor 3b, subunit 5, 10kDa".

Further reading

Mehrle A, Rosenfelder H, Schupp I, et al. (2006). "The LIFEdb database in 2006". Nucleic Acids Res. 34 (Database issue): D415–8. doi:10.1093/nar/gkj139. PMC 1347501. PMID 16381901.
Wiemann S, Arlt D, Huber W, et al. (2004). "From ORFeome to biology: a functional genomics pipeline". Genome Res. 14 (10B): 2136–44. doi:10.1101/gr.2576704. PMC 528930. PMID 15489336.
Gerhard DS, Wagner L, Feingold EA, et al. (2004). "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)". Genome Res. 14 (10B): 2121–7. doi:10.1101/gr.2596504. PMC 528928. PMID 15489334.
Mungall AJ, Palmer SA, Sims SK, et al. (2003). "The DNA sequence and analysis of human chromosome 6". Nature. 425 (6960): 805–11. Bibcode:2003Natur.425..805M. doi:10.1038/nature02055. PMID 14574404.
Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. Bibcode:2002PNAS...9916899M. doi:10.1073/pnas.242603899. PMC 139241. PMID 12477932.
Simpson JC, Wellenreuther R, Poustka A, et al. (2001). "Systematic subcellular localization of novel proteins identified by large-scale cDNA sequencing". EMBO Rep. 1 (3): 287–92. doi:10.1093/embo-reports/kvd058. PMC 1083732. PMID 11256614.
Hartley JL, Temple GF, Brasch MA (2001). "DNA cloning using in vitro site-specific recombination". Genome Res. 10 (11): 1788–95. doi:10.1101/gr.143000. PMC 310948. PMID 11076863.

[refGRCh38Ensembl-1] GRCh38: Ensembl release 89: ENSG00000169976 – Ensembl, May 2017

[refGRCm38Ensembl-2] GRCm38: Ensembl release 89: ENSMUSG00000078348 – Ensembl, May 2017

[3] "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[4] "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[pmid12234937-5] Will CL, Urlaub H, Achsel T, Gentzel M, Wilm M, Luhrmann R (Sep 2002). "Characterization of novel SF3b and 17S U2 snRNP proteins, including a human Prp5p homologue and an SF3b DEAD-box protein". EMBO J. 21 (18): 4978–88. doi:10.1093/emboj/cdf480. PMC 126279. PMID 12234937.

[entrez-6] "Entrez Gene: SF3B5 splicing factor 3b, subunit 5, 10kDa".

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