SARNP

SARNP
Available structures
PDB	Ortholog search: PDBe RCSB
List of PDB id codes
	2DO1
Identifiers
Aliases	SARNP, CIP29, HCC1, HSPC316, THO1, SAP domain containing ribonucleoprotein
External IDs	OMIM: 610049; MGI: 1913368; HomoloGene: 41628; GeneCards: SARNP; OMA:SARNP - orthologs
Gene location (Mouse)
Chr.	Chromosome 10 (mouse)
End	128,877,629 bp
RNA expression pattern
	Top expressed in
	ganglionic eminence; ; smooth muscle tissue; ; Achilles tendon; ; monocyte; ; tibial nerve; ; right adrenal gland; ; ascending aorta; ; islet of Langerhans; ; gastrocnemius muscle; ; left coronary artery;
	Top expressed in
	ventricular zone; ; ganglionic eminence; ; epiblast; ; lens; ; neural tube; ; yolk sac; ; ovary; ; thymus; ; embryo; ; embryo;
	More reference expression data
	; ;
	More reference expression data
Gene ontology
Molecular function	DNA binding; protein binding; RNA binding; RNA polymerase II cis-regulatory region sequence-specific DNA binding; DNA-binding transcription repressor activity, RNA polymerase II-specific; protein C-terminus binding; RS domain binding;
Cellular component	nuclear speck; transcription export complex; nucleus; nucleoplasm; cytoplasmic ribonucleoprotein granule;
Biological process	mRNA transport; regulation of transcription, DNA-templated; regulation of translation; transcription, DNA-templated; RNA export from nucleus; mRNA export from nucleus; termination of RNA polymerase II transcription; mRNA 3'-end processing; transport; negative regulation of transcription by RNA polymerase II;
	Sources:Amigo / QuickGO
Orthologs
	84324
	66118
	n/a
	ENSMUSG00000078427
	P82979
	Q9D1J3
	NM_033082
	NM_025364
	NP_149073
NP_079640; NP_001346332; NP_001346333; NP_001346334; NP_001346335;
	NP_001346336
	Wikidata
View/Edit Human	View/Edit Mouse

SAP domain-containing ribonucleoprotein is a protein that in humans is encoded by the SARNP gene.⁴⁵⁶

References

GRCm38: Ensembl release 89: ENSMUSG00000078427 – Ensembl, May 2017
"Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
"Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
Choong ML, Tan LK, Lo SL, Ren EC, Ou K, Ong SE, Liang RC, Seow TK, Chung MC (May 2001). "An integrated approach in the discovery and characterization of a novel nuclear protein over-expressed in liver and pancreatic tumors". FEBS Lett. 496 (2–3): 109–16. Bibcode:2001FEBSL.496..109C. doi:10.1016/S0014-5793(01)02409-7. PMID 11356193. S2CID 24122700.
Fukuda S, Wu DW, Stark K, Pelus LM (Mar 2002). "Cloning and characterization of a proliferation-associated cytokine-inducible protein, CIP29". Biochem Biophys Res Commun. 292 (3): 593–600. doi:10.1006/bbrc.2002.6680. PMID 11922608.
"Entrez Gene: CIP29 cytokine induced protein 29 kDa".

External links

Human SARNP genome location and SARNP gene details page in the UCSC Genome Browser.

Further reading

Maruyama K, Sugano S (1994). "Oligo-capping: a simple method to replace the cap structure of eukaryotic mRNAs with oligoribonucleotides". Gene. 138 (1–2): 171–4. doi:10.1016/0378-1119(94)90802-8. PMID 8125298.
Suzuki Y, Yoshitomo-Nakagawa K, Maruyama K, et al. (1997). "Construction and characterization of a full length-enriched and a 5'-end-enriched cDNA library". Gene. 200 (1–2): 149–56. doi:10.1016/S0378-1119(97)00411-3. PMID 9373149.
Zhang QH, Ye M, Wu XY, et al. (2001). "Cloning and functional analysis of cDNAs with open reading frames for 300 previously undefined genes expressed in CD34+ hematopoietic stem/progenitor cells". Genome Res. 10 (10): 1546–60. doi:10.1101/gr.140200. PMC 310934. PMID 11042152.
Andersen JS, Lyon CE, Fox AH, et al. (2002). "Directed proteomic analysis of the human nucleolus". Curr. Biol. 12 (1): 1–11. Bibcode:2002CBio...12....1A. doi:10.1016/S0960-9822(01)00650-9. PMID 11790298. S2CID 14132033.
Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. Bibcode:2002PNAS...9916899M. doi:10.1073/pnas.242603899. PMC 139241. PMID 12477932.
Lehner B, Semple JI, Brown SE, et al. (2004). "Analysis of a high-throughput yeast two-hybrid system and its use to predict the function of intracellular proteins encoded within the human MHC class III region". Genomics. 83 (1): 153–67. doi:10.1016/S0888-7543(03)00235-0. PMID 14667819.
Navakauskiene R, Treigyte G, Gineitis A, Magnusson KE (2004). "Identification of apoptotic tyrosine-phosphorylated proteins after etoposide or retinoic acid treatment". Proteomics. 4 (4): 1029–41. doi:10.1002/pmic.200300671. PMID 15048984. S2CID 26389150.
Hashii Y, Kim JY, Sawada A, et al. (2004). "A novel partner gene CIP29 containing a SAP domain with MLL identified in infantile myelomonocytic leukemia". Leukemia. 18 (9): 1546–8. doi:10.1038/sj.leu.2403450. PMID 15284855. S2CID 23982148.
Leaw CL, Ren EC, Choong ML (2004). "Hcc-1 is a novel component of the nuclear matrix with growth inhibitory function". Cell. Mol. Life Sci. 61 (17): 2264–73. doi:10.1007/s00018-004-4205-x. PMC 11138947. PMID 15338056. S2CID 19729441.
Gerhard DS, Wagner L, Feingold EA, et al. (2004). "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)". Genome Res. 14 (10B): 2121–7. doi:10.1101/gr.2596504. PMC 528928. PMID 15489334.
Andersen JS, Lam YW, Leung AK, et al. (2005). "Nucleolar proteome dynamics". Nature. 433 (7021): 77–83. Bibcode:2005Natur.433...77A. doi:10.1038/nature03207. PMID 15635413. S2CID 4344740.
Rual JF, Venkatesan K, Hao T, et al. (2005). "Towards a proteome-scale map of the human protein-protein interaction network". Nature. 437 (7062): 1173–8. Bibcode:2005Natur.437.1173R. doi:10.1038/nature04209. PMID 16189514. S2CID 4427026.
Sugiura T, Sakurai K, Nagano Y (2007). "Intracellular characterization of DDX39, a novel growth-associated RNA helicase". Exp. Cell Res. 313 (4): 782–90. doi:10.1016/j.yexcr.2006.11.014. PMID 17196963.

[refGRCm38Ensembl-1] GRCm38: Ensembl release 89: ENSMUSG00000078427 – Ensembl, May 2017

[2] "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[3] "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[pmid11356193-4] Choong ML, Tan LK, Lo SL, Ren EC, Ou K, Ong SE, Liang RC, Seow TK, Chung MC (May 2001). "An integrated approach in the discovery and characterization of a novel nuclear protein over-expressed in liver and pancreatic tumors". FEBS Lett. 496 (2–3): 109–16. Bibcode:2001FEBSL.496..109C. doi:10.1016/S0014-5793(01)02409-7. PMID 11356193. S2CID 24122700.

[pmid11922608-5] Fukuda S, Wu DW, Stark K, Pelus LM (Mar 2002). "Cloning and characterization of a proliferation-associated cytokine-inducible protein, CIP29". Biochem Biophys Res Commun. 292 (3): 593–600. doi:10.1006/bbrc.2002.6680. PMID 11922608.

[entrez-6] "Entrez Gene: CIP29 cytokine induced protein 29 kDa".

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