RRP9

RRP9
Available structures
PDB	Ortholog search: PDBe RCSB
List of PDB id codes
	4J0W, 4JXM
Identifiers
Aliases	RRP9, RNU3IP2, U3-55K, ribosomal RNA processing 9, small subunit (SSU) processome component, homolog (yeast), ribosomal RNA processing 9, U3 small nucleolar RNA binding protein
External IDs	MGI: 2384313; HomoloGene: 3452; GeneCards: RRP9; OMA:RRP9 - orthologs
Gene location (Human)
Chr.	Chromosome 3 (human)
End	51,941,904 bp
Gene location (Mouse)
Chr.	Chromosome 9 (mouse)
End	106,362,623 bp
RNA expression pattern
	Top expressed in
	gastrocnemius muscle; ; mucosa of transverse colon; ; left adrenal cortex; ; left uterine tube; ; right adrenal gland; ; right adrenal cortex; ; muscle of thigh; ; ectocervix; ; right ovary; ; granulocyte;
	Top expressed in
	yolk sac; ; neural layer of retina; ; embryo; ; embryo; ; morula; ; epiblast; ; perirhinal cortex; ; ventricular zone; ; entorhinal cortex; ; muscle of thigh;
	More reference expression data
	More reference expression data
Gene ontology
Molecular function	U3 snoRNA binding; RNA binding; snoRNA binding;
Cellular component	small-subunit processome; nucleolus; box C/D RNP complex; nucleoplasm; nucleus;
Biological process	rRNA processing;
	Sources:Amigo / QuickGO
Orthologs
	9136
	27966
	ENSG00000114767
	ENSMUSG00000041506
	O43818
	Q91WM3
	NM_004704
	NM_145620
	NP_004695
	NP_663595
	Wikidata
View/Edit Human	View/Edit Mouse

U3 small nucleolar RNA-interacting protein 2 is a protein that in humans is encoded by the RRP9 gene.⁵⁶⁷

References

GRCh38: Ensembl release 89: ENSG00000114767 – Ensembl, May 2017
GRCm38: Ensembl release 89: ENSMUSG00000041506 – Ensembl, May 2017
"Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
"Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
Pluk H, Soffner J, Luhrmann R, van Venrooij WJ (Jan 1998). "cDNA Cloning and Characterization of the Human U3 Small Nucleolar Ribonucleoprotein Complex-Associated 55-Kilodalton Protein". Mol Cell Biol. 18 (1): 488–98. doi:10.1128/mcb.18.1.488. PMC 121518. PMID 9418896.
Verheggen C, Lafontaine DL, Samarsky D, Mouaikel J, Blanchard JM, Bordonne R, et al. (May 2002). "Mammalian and yeast U3 snoRNPs are matured in specific and related nuclear compartments". EMBO J. 21 (11): 2736–45. doi:10.1093/emboj/21.11.2736. PMC 126019. PMID 12032086.
"Entrez Gene: RRP9 RRP9, small subunit (SSU) processome component, homolog (yeast)".

Further reading

Lukowiak AA, Granneman S, Mattox SA, Speckmann WA, Jones K, Pluk H, et al. (2000). "Interaction of the U3-55k protein with U3 snoRNA is mediated by the Box B/C motif of U3 and the WD repeats of U3-55k". Nucleic Acids Res. 28 (18): 3462–71. doi:10.1093/nar/28.18.3462. PMC 110750. PMID 10982864.
Andersen JS, Lyon CE, Fox AH, Leung AK, Lam YW, Steen H, et al. (2002). "Directed proteomic analysis of the human nucleolus". Curr. Biol. 12 (1): 1–11. Bibcode:2002CBio...12....1A. doi:10.1016/S0960-9822(01)00650-9. PMID 11790298. S2CID 14132033.
Granneman S, Pruijn GJ, Horstman W, Van Venrooij WJ, Luhrmann R, Watkins NJ (2003). "The hU3-55K protein requires 15.5K binding to the box B/C motif as well as flanking RNA elements for its association with the U3 small nucleolar RNA in Vitro". J. Biol. Chem. 277 (50): 48490–500. doi:10.1074/jbc.M206631200. hdl:11858/00-001M-0000-0012-F261-B. PMID 12381732.
Scherl A, Couté Y, Déon C, Callé A, Kindbeiter K, Sanchez JC, et al. (2003). "Functional Proteomic Analysis of Human Nucleolus". Mol. Biol. Cell. 13 (11): 4100–9. doi:10.1091/mbc.E02-05-0271. PMC 133617. PMID 12429849.
Strausberg RL, Feingold EA, Grouse LH, Derge JG, Klausner RD, Collins FS, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. Bibcode:2002PNAS...9916899M. doi:10.1073/pnas.242603899. PMC 139241. PMID 12477932.
Gerhard DS, Wagner L, Feingold EA, Shenmen CM, Grouse LH, Schuler G, et al. (2004). "The Status, Quality, and Expansion of the NIH Full-Length cDNA Project: The Mammalian Gene Collection (MGC)". Genome Res. 14 (10B): 2121–7. doi:10.1101/gr.2596504. PMC 528928. PMID 15489334.
Watkins NJ, Lemm I, Ingelfinger D, Schneider C, Hoßbach M, Urlaub H, et al. (2005). "Assembly and maturation of the U3 snoRNP in the nucleoplasm in a large dynamic multiprotein complex". Mol. Cell. 16 (5): 789–98. doi:10.1016/j.molcel.2004.11.012. hdl:11858/00-001M-0000-0012-EB89-8. PMID 15574333.
Andersen JS, Lam YW, Leung AK, Ong SE, Lyon CE, Lamond AI, et al. (2005). "Nucleolar proteome dynamics". Nature. 433 (7021): 77–83. Bibcode:2005Natur.433...77A. doi:10.1038/nature03207. PMID 15635413. S2CID 4344740.
Barrios-Rodiles M, Brown KR, Ozdamar B, Bose R, Liu Z, Donovan RS, et al. (2005). "High-throughput mapping of a dynamic signaling network in mammalian cells". Science. 307 (5715): 1621–5. Bibcode:2005Sci...307.1621B. doi:10.1126/science.1105776. PMID 15761153. S2CID 39457788.
Olsen JV, Blagoev B, Gnad F, Macek B, Kumar C, Mortensen P, et al. (2006). "Global, in vivo, and site-specific phosphorylation dynamics in signaling networks". Cell. 127 (3): 635–48. doi:10.1016/j.cell.2006.09.026. PMID 17081983. S2CID 7827573.

External links

PDBe-KB provides an overview of all the structure information available in the PDB for Human U3 small nucleolar RNA-interacting protein 2 (RRP9)

[refGRCh38Ensembl-1] GRCh38: Ensembl release 89: ENSG00000114767 – Ensembl, May 2017

[refGRCm38Ensembl-2] GRCm38: Ensembl release 89: ENSMUSG00000041506 – Ensembl, May 2017

[3] "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[4] "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[pmid9418896-5] Pluk H, Soffner J, Luhrmann R, van Venrooij WJ (Jan 1998). "cDNA Cloning and Characterization of the Human U3 Small Nucleolar Ribonucleoprotein Complex-Associated 55-Kilodalton Protein". Mol Cell Biol. 18 (1): 488–98. doi:10.1128/mcb.18.1.488. PMC 121518. PMID 9418896.

[pmid12032086-6] Verheggen C, Lafontaine DL, Samarsky D, Mouaikel J, Blanchard JM, Bordonne R, et al. (May 2002). "Mammalian and yeast U3 snoRNPs are matured in specific and related nuclear compartments". EMBO J. 21 (11): 2736–45. doi:10.1093/emboj/21.11.2736. PMC 126019. PMID 12032086.

[entrez-7] "Entrez Gene: RRP9 RRP9, small subunit (SSU) processome component, homolog (yeast)".

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See also

References

Further reading

External links