Article · Wikipedia archive · Last revised Jun 15, 2026

Raphanin

Raphanin is the main sulfur component found in radish seeds of Raphanus sativus and is also found in broccoli and red cabbage. It was first described in 1947.

Last revised
Jun 15, 2026
Read time
≈ 1 min
Length
313 w
Citations
8
Source
Wikipedia ↗
Raphanin
source ↗
Names
Preferred IUPAC name
(1E)-4-Isothiocyanato-1-(methanesulfinyl)but-1-ene
Other names
Sulforaphen; Sulforaphene; Sativin
Identifiers
3D model (JSmol)
ChemSpider
UNII
  • InChI=1S/C6H9NOS2/c1-10(8)5-3-2-4-7-6-9/h3,5H,2,4H2,1H3
    Key: QKGJFQMGPDVOQE-UHFFFAOYSA-N
  • InChI=1/C6H9NOS2/c1-10(8)5-3-2-4-7-6-9/h3,5H,2,4H2,1H3
    Key: QKGJFQMGPDVOQE-UHFFFAOYAU
  • S=C=N/CC\C=C\S(=O)C
Properties
C6H9NOS2
Molar mass 175.26 g·mol−1
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).

Raphanin is the main sulfur component found in radish seeds of Raphanus sativus and is also found in broccoli and red cabbage.12 It was first described in 1947.34

Basic research

In vitro, raphanin inhibits some fungi and various bacteria including Staphylococcus, Streptococcus, Pneumococcus and Escherichia coli.356

Minimum inhibitory concentration of raphanin7
Bacteria MIC (mg/mL)
Staphylococcus 0.04
Shigella dysenteriae 0.125
Salmonella typhi 0.125
Escherichia coli 0.2
See also

See also

References

References

  1. Sinha, Nirmal K.; Hui, Y. H.; Muhammad Siddiq; Jasim Ahmed (2010). Handbook of Vegetables and Vegetable Processing. John Wiley and Sons. p. 156. ISBN 978-0-8138-1541-1.
  2. Michael Meyer & Sieghard T. Adam (2008). "Comparison of glucosinolate levels in commercial broccoli and red cabbage from conventional and ecological farming". European Food Research and Technology. 226 (6): 1429–1437. doi:10.1007/s00217-007-0674-0. S2CID 98687281.
  3. Baron, Abraham Louis (1950). Handbook of antibiotics. Reinhold. p. 215. ISBN 9780598986818. {{cite book}}: ISBN / Date incompatibility (help)
  4. Ivãnovics, G. & S. Horvãth (1947). "Raphanin, an Antibacterial Principle of the Radish (Raphanus sativus)". Nature. 160 (4061): 297–298. Bibcode:1947Natur.160..297I. doi:10.1038/160297a0. PMID 20261763. S2CID 4005718.
  5. Florey, Howard (1949). Antibiotics: a survey of penicillin, streptomycin, and other antimicrobial substances from fungi, actinomycetes, bacteria, and plants. Oxford University Press. pp. 625–6.
  6. Ivànovics, G. & Horvath, S. (1947). "Isolation and Properties of Raphanin, an Antibacterial Substance from Radish Seed". Experimental Biology and Medicine. 66 (3): 625–630. doi:10.3181/00379727-66-16177. PMID 18900045. S2CID 32292410.
  7. Chang, Hson-Mou; Pui-Hay, Paul; Yao, Sih-Cheng (2001). Pharmacology and Applications of Chinese Material Medical. World Scientific. p. 969. ISBN 978-981-02-3694-6.