Quake may refer to:
Seismology
- Earthquake, a shaking of the Earth's surface
- Quake (natural phenomenon), surface shaking on any astronomical body
Arts and entertainment
- Quake (album), a 2003 album by Erik Friedlander
- Quake (1992 film), an American direct-to-video film
- Quake (2021 film), an Icelandic drama film
- The Quake (film), a 2018 Norwegian film
- Quake (series), a series of first-person shooter games
- Quake (video game), the 1996 first game in the series
- Quake engine, a game engine by ID Software, first used in the 1996 game
- Quake (original soundtrack), by Trent Reznor and Nine Inch Nails, 1996
- Quake II engine, the 1997 second iteration of the game engine, first used in Quake II
- Quake (video game), the 1996 first game in the series
- WQKE, The Quake, an FM radio station in Plattsburgh, New York, US
- Quake, a Transformers comics character
- Quake, a superhero code name used by the Marvel Comics character Daisy Johnson
- Quake: Youth Encountering the Gospel, a Christian youth event hosted across the United States
Other uses
- Quake (cereal), a breakfast cereal marketed with Quisp
- Quake Inc., now Exit Tunes, Inc., a Japanese media company
- Quake Lake, a lake in Montana, US
- Stephen Quake (born 1969), American scientist