Article · Wikipedia archive · Last revised Jun 2, 2026

PRH1

Salivary acidic proline-rich phosphoprotein 1/2 is a protein that in humans is encoded by the PRH1 gene.

Last revised

Jun 2, 2026

Read time

≈ 1 min

Length

240 w

Citations

6

Source

PRH1

Identifiers

PRH1, PA, Db-s, PIF-S, PRH2, Pr1/Pr2, proline-rich protein HaeIII subfamily 1, proline rich protein HaeIII subfamily 1, PRP-1/PRP-2

External IDs

OMIM: 168730; GeneCards: PRH1; OMA:PRH1 - orthologs

Gene location (Human)

Chr.	Chromosome 12 (human)¹

Band	12p13.2	Start	10,824,960 bp¹
Band	12p13.2	End	11,171,608 bp¹

RNA expression pattern

Human

Mouse (ortholog)

Top expressed in

left testis

right testis

corpus callosum

testicle

Achilles tendon

bone marrow cell

gonad

tonsil

epithelium of colon

olfactory zone of nasal mucosa

n/a

More reference expression data

n/a

Species

Human

Mouse


5554


n/a


ENSG00000231887 ENSG00000277823


n/a


P02810


n/a

RefSeq (mRNA)


NM_006250 NM_001291314 NM_001291315 NM_001393989


n/a

RefSeq (protein)


NP_001103683


n/a

Location (UCSC)

Chr 12: 10.82 – 11.17 Mb

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PubMed search

²

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View/Edit Human

Salivary acidic proline-rich phosphoprotein 1/2 is a protein that in humans is encoded by the PRH1 gene.³⁴

References

References

ENSG00000277823 GRCh38: Ensembl release 89: ENSG00000231887, ENSG00000277823 – Ensembl, May 2017
"Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
Kim HS, Maeda N (Jun 1986). "Structures of two HaeIII-type genes in the human salivary proline-rich protein multigene family". J Biol Chem. 261 (15): 6712–8. doi:10.1016/S0021-9258(19)62674-8. PMID 3009472.
"Entrez Gene: PRH1 proline-rich protein HaeIII subfamily 1".

Further reading

Further reading

Friedman RD, Merritt AD (1990). "Partial purification and characterization of a polymorphic protein (Pa) in human parotid saliva". Am. J. Hum. Genet. 27 (3): 304–14. PMC 1762868. PMID 803013.
Maeda N, Kim HS, Azen EA, Smithies O (1985). "Differential RNA splicing and post-translational cleavages in the human salivary proline-rich protein gene system". J. Biol. Chem. 260 (20): 11123–30. doi:10.1016/S0021-9258(17)39156-1. PMID 2993301.
Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. Bibcode:2002PNAS...9916899M. doi:10.1073/pnas.242603899. PMC 139241. PMID 12477932.