Article · Wikipedia archive · Last revised Jun 19, 2026

Preprohormone

A preprohormone is the precursor protein to one or more prohormones, which are in turn precursors to peptide hormones. In general, the protein consists of the amino acid chain that is created by the hormone-secreting cell, before any changes have been made to it. It contains a signal peptide, the hormone(s) itself (themselves), and intervening amino acids. Before the hormone is released from the cell, the signal peptide and other amino acids are removed.

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A preprohormone is the precursor protein to one or more prohormones, which are in turn precursors to peptide hormones.1 In general, the protein consists of the amino acid chain that is created by the hormone-secreting cell, before any changes have been made to it. It contains a signal peptide, the hormone(s) itself (themselves), and intervening amino acids. Before the hormone is released from the cell, the signal peptide and other amino acids are removed.23

See also

See also

References

References

  1. Voet, Donald; Voet, Judith (2010). Biochemistry (4th ed.). Hoboken, NJ: John Wiley & Sons. p. 675. ISBN 9780470570951.
  2. "Introduction to Endocrine Physiology". courses.washington.edu. University of Washington. Retrieved 17 November 2017.
  3. Owens, Anthony (23 June 2017). "Prohormones: Effects, Risks, and Legality". prohormones.co. Retrieved 17 November 2017.