Phosalone

Phosalone
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Names
	Preferred IUPAC name S-[(6-Chloro-2-oxo-1,3-benzoxazol-3(2H)-yl)methyl] O,O-diethyl phosphorodithioate
	Other names Zolone
Identifiers
CAS Number	2310-17-0 Y;
3D model (JSmol)	Interactive image;
ChEBI	CHEBI:8121 Y;
ChEMBL	ChEMBL1528531 N;
ChemSpider	4629 Y;
ECHA InfoCard	100.017.270
KEGG	C11028 Y;
PubChem CID	4793;
UNII	448B85HT8M Y;
CompTox Dashboard (EPA)	DTXSID1024259 ;
	InChI InChI=1S/C12H15ClNO4PS2/c1-3-16-19(20,17-4-2)21-8-14-10-6-5-9(13)7-11(10)18-12(14)15/h5-7H,3-4,8H2,1-2H3 Y Key: IOUNQDKNJZEDEP-UHFFFAOYSA-N Y; InChI=1/C12H15ClNO4PS2/c1-3-16-19(20,17-4-2)21-8-14-10-6-5-9(13)7-11(10)18-12(14)15/h5-7H,3-4,8H2,1-2H3 Key: IOUNQDKNJZEDEP-UHFFFAOYAA;
	SMILES Clc2ccc1c(OC(=O)N1CSP(=S)(OCC)OCC)c2;
Properties
Chemical formula	C12H15ClNO4PS2
Molar mass	367.80 g·mol−1
Appearance	Colorless crystalline
Odor	garlic
Density	1.39 g cm−3
Melting point	47.5 to 48 °C (117.5 to 118.4 °F; 320.6 to 321.1 K)
Solubility in water	3.05 mg/L
Solubility	many organic solvents
	Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa). N verify (what is YN ?) Infobox references

Phosalone is an organophosphate chemical commonly used as an insecticide and acaricide. It is developed by Rhône-Poulenc in France but EU eliminated it from pesticide registration in December 2006.

The median lethal dose of oral exposure in rat is 85 mg/kg and that of dermal is 390 mg/kg.¹。It is a weak acetylcholinesterase inhibitor.² It is taken by not only oral and inhalation but skin and it causes toxic symptoms peculiar to organophosphorus compounds such as miosis, hypersalivation, hyperhidrosis, chest pressure, pulmonary edema and fecal incontinence.³ It is flammable and decomposes to toxic gases such as phosphorus oxides, sulfur oxides and nitrogen oxides.² It is harmful especially to water creatures.

References

製品安全データシート（安全衛生情報センター） Archived 2014-10-25 at the Wayback Machine
"国際化学物質安全性カード". Archived from the original on 2012-12-11. Retrieved 2012-09-06.
植村振作・河村宏・辻万千子・冨田重行・前田静夫著 (2002). 農薬毒性の事典改訂版. 三省堂. ISBN 978-4385356044.

External links

Phosalone Fact Sheet Archived 2005-03-09 at the Wayback Machine
EPA Webpage on Phosolone
Phosalone in the Pesticide Properties DataBase (PPDB)

[Jaish-1] 製品安全データシート（安全衛生情報センター） Archived 2014-10-25 at the Wayback Machine

[nihs-2] "国際化学物質安全性カード". Archived from the original on 2012-12-11. Retrieved 2012-09-06.

[Sanseido-3] 植村振作・河村宏・辻万千子・冨田重行・前田静夫著 (2002). 農薬毒性の事典改訂版. 三省堂. ISBN 978-4385356044.

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