OBSL1

OBSL1
Available structures
PDB	Ortholog search: PDBe RCSB
List of PDB id codes
	2CPC, 2E6P, 2E6Q, 2LU7, 2LVC, 2WP3, 2WWK, 2WWM, 3KNB
Identifiers
Aliases	OBSL1, obscurin like 1, obscurin like cytoskeletal adaptor 1
External IDs	OMIM: 610991; MGI: 2138628; HomoloGene: 28013; GeneCards: OBSL1; OMA:OBSL1 - orthologs
Gene location (Human)
Chr.	Chromosome 2 (human)
End	219,571,859 bp
Gene location (Mouse)
Chr.	Chromosome 1 (mouse)
End	75,483,096 bp
RNA expression pattern
	Top expressed in
	right testis; ; left testis; ; left ovary; ; right ovary; ; right lobe of thyroid gland; ; left lobe of thyroid gland; ; right adrenal cortex; ; right uterine tube; ; apex of heart; ; right hemisphere of cerebellum;
	Top expressed in
	yolk sac; ; internal carotid artery; ; external carotid artery; ; fossa; ; muscle of thigh; ; condyle; ; vas deferens; ; renal corpuscle; ; genital tubercle; ; medullary collecting duct;
	More reference expression data
	; ; ; ;
	More reference expression data
Gene ontology
Molecular function	cytoskeletal anchor activity; protein binding; structural constituent of muscle; actin filament binding; muscle alpha-actinin binding; structural molecule activity conferring elasticity;
Cellular component	Z discdkac; 3M complex; intercalated disc; M band; centrosome; microtubule organizing center; cytoskeleton; cytoplasm; Golgi apparatus; perinuclear region of cytoplasm; muscle myosin complex; cytosol; striated muscle thin filament; sarcomere;
Biological process	protein localization to Golgi apparatus; cardiac myofibril assembly; microtubule cytoskeleton organization; cytoskeleton organization; regulation of mitotic nuclear division; positive regulation of dendrite morphogenesis; Golgi organization; striated muscle contraction; actin filament organization; sarcomere organization; striated muscle myosin thick filament assembly; post-translational protein modification; muscle contraction; skeletal muscle thin filament assembly; skeletal muscle myosin thick filament assembly; cardiac muscle tissue morphogenesis;
	Sources:Amigo / QuickGO
Orthologs
	23363
	98733
	ENSG00000124006
	ENSMUSG00000026211
	O75147
	D3YYU8
	NM_001173408; NM_001173431; NM_015311
	NM_178884; NM_001310679
	NP_001166879; NP_001166902; NP_056126
	NP_001297608; NP_849215; NP_001390042; NP_001390043
	Wikidata
View/Edit Human	View/Edit Mouse

Obscurin-like protein 1 is a protein that in humans is encoded by the OBSL1 gene.⁵⁶

References

GRCh38: Ensembl release 89: ENSG00000124006 – Ensembl, May 2017
GRCm38: Ensembl release 89: ENSMUSG00000026211 – Ensembl, May 2017
"Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
"Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
Ishikawa K, Nagase T, Suyama M, Miyajima N, Tanaka A, Kotani H, Nomura N, Ohara O (Dec 1998). "Prediction of the coding sequences of unidentified human genes. X. The complete sequences of 100 new cDNA clones from brain which can code for large proteins in vitro". DNA Res. 5 (3): 169–76. doi:10.1093/dnares/5.3.169. PMID 9734811.
"Entrez Gene: OBSL1 obscurin-like 1".

External links

GeneReviews/NIH/NCBI/UW entry on 3-M syndrome
OMIM entries on 3-M syndrome
PDBe-KB provides an overview of all the structure information available in the PDB for Human Obscurin-like protein 1 (OBSL1)

[refGRCh38Ensembl-1] GRCh38: Ensembl release 89: ENSG00000124006 – Ensembl, May 2017

[refGRCm38Ensembl-2] GRCm38: Ensembl release 89: ENSMUSG00000026211 – Ensembl, May 2017

[3] "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[4] "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[pmid9734811-5] Ishikawa K, Nagase T, Suyama M, Miyajima N, Tanaka A, Kotani H, Nomura N, Ohara O (Dec 1998). "Prediction of the coding sequences of unidentified human genes. X. The complete sequences of 100 new cDNA clones from brain which can code for large proteins in vitro". DNA Res. 5 (3): 169–76. doi:10.1093/dnares/5.3.169. PMID 9734811.

[entrez-6] "Entrez Gene: OBSL1 obscurin-like 1".

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References

Further reading

External links