NIP7

NIP7
Available structures
PDB	Ortholog search: PDBe RCSB
List of PDB id codes
	1SQW, 1T5Y
Identifiers
Aliases	NIP7, HSPC031, KD93, CGI-37, nucleolar pre-rRNA processing protein, nucleolar pre-rRNA processing protein NIP7
External IDs	MGI: 1913414; HomoloGene: 56743; GeneCards: NIP7; OMA:NIP7 - orthologs
Gene location (Human)
Chr.	Chromosome 16 (human)
End	69,343,106 bp
Gene location (Mouse)
Chr.	Chromosome 8 (mouse)
End	107,787,563 bp
RNA expression pattern
	Top expressed in
	secondary oocyte; ; mucosa of pharynx; ; oral cavity; ; gonad; ; islet of Langerhans; ; nipple; ; gums; ; superior surface of tongue; ; rectum; ; gingival epithelium;
	Top expressed in
	endocardial cushion; ; somite; ; epiblast; ; primitive streak; ; mandibular prominence; ; maxillary prominence; ; abdominal wall; ; otic placode; ; embryo; ; migratory enteric neural crest cell;
	More reference expression data
	More reference expression data
Gene ontology
Molecular function	protein binding; RNA binding;
Cellular component	nucleus; nucleolus; preribosome, large subunit precursor; cytosol;
Biological process	ribosome biogenesis; ribosome assembly; ribosomal large subunit biogenesis;
	Sources:Amigo / QuickGO
Orthologs
	51388
	66164
	ENSG00000132603
	ENSMUSG00000031917
	Q9Y221
	Q9CXK8
	NM_016101; NM_001199434
	NM_001164472; NM_025391
	NP_001186363; NP_057185
	NP_001157944; NP_079667
	Wikidata
View/Edit Human	View/Edit Mouse

60S ribosome subunit biogenesis protein NIP7 homolog is a protein that in humans is encoded by the NIP7 gene.⁵⁶

Interactions

NIP7 has been shown to interact with NOL8.⁵

References

GRCh38: Ensembl release 89: ENSG00000132603 – Ensembl, May 2017
GRCm38: Ensembl release 89: ENSMUSG00000031917 – Ensembl, May 2017
"Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
"Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
Sekiguchi T, Todaka Y, Wang Y, Hirose E, Nakashima N, Nishimoto T (Feb 2004). "A novel human nucleolar protein, Nop132, binds to the G proteins, RRAG A/C/D". J Biol Chem. 279 (9): 8343–50. doi:10.1074/jbc.M305935200. PMID 14660641.
"Entrez Gene: NIP7 nuclear import 7 homolog (S. cerevisiae)".

Further reading

Lai CH, Chou CY, Ch'ang LY, Liu CS, Lin W (2000). "Identification of novel human genes evolutionarily conserved in Caenorhabditis elegans by comparative proteomics". Genome Res. 10 (5): 703–13. doi:10.1101/gr.10.5.703. PMC 310876. PMID 10810093.
Zhang QH, Ye M, Wu XY, Ren SX, Zhao M, Zhao CJ, Fu G, Shen Y, Fan HY, Lu G, Zhong M, Xu XR, Han ZG, Zhang JW, Tao J, Huang QH, Zhou J, Hu GX, Gu J, Chen SJ, Chen Z (2001). "Cloning and functional analysis of cDNAs with open reading frames for 300 previously undefined genes expressed in CD34+ hematopoietic stem/progenitor cells". Genome Res. 10 (10): 1546–60. doi:10.1101/gr.140200. PMC 310934. PMID 11042152.
Chagnon P, Michaud J, Mitchell G, Mercier J, Marion JF, Drouin E, Rasquin-Weber A, Hudson TJ, Richter A (2003). "A missense mutation (R565W) in cirhin (FLJ14728) in North American Indian childhood cirrhosis". Am. J. Hum. Genet. 71 (6): 1443–9. doi:10.1086/344580. PMC 378590. PMID 12417987.
Scherl A, Couté Y, Déon C, Callé A, Kindbeiter K, Sanchez JC, Greco A, Hochstrasser D, Diaz JJ (2003). "Functional proteomic analysis of human nucleolus". Mol. Biol. Cell. 13 (11): 4100–9. doi:10.1091/mbc.E02-05-0271. PMC 133617. PMID 12429849.
Liu JF, Wang XQ, Wang ZX, Chen JR, Jiang T, An XM, Chang WR, Liang DC (2005). "Crystal structure of KD93, a novel protein expressed in human hematopoietic stem/progenitor cells". J. Struct. Biol. 148 (3): 370–4. doi:10.1016/j.jsb.2004.06.010. PMID 15522784.
Andersen JS, Lam YW, Leung AK, Ong SE, Lyon CE, Lamond AI, Mann M (2005). "Nucleolar proteome dynamics". Nature. 433 (7021): 77–83. Bibcode:2005Natur.433...77A. doi:10.1038/nature03207. PMID 15635413. S2CID 4344740.
Rual JF, Venkatesan K, Hao T, Hirozane-Kishikawa T, Dricot A, Li N, Berriz GF, Gibbons FD, Dreze M, Ayivi-Guedehoussou N, Klitgord N, Simon C, Boxem M, Milstein S, Rosenberg J, Goldberg DS, Zhang LV, Wong SL, Franklin G, Li S, Albala JS, Lim J, Fraughton C, Llamosas E, Cevik S, Bex C, Lamesch P, Sikorski RS, Vandenhaute J, Zoghbi HY, Smolyar A, Bosak S, Sequerra R, Doucette-Stamm L, Cusick ME, Hill DE, Roth FP, Vidal M (2005). "Towards a proteome-scale map of the human protein-protein interaction network". Nature. 437 (7062): 1173–8. Bibcode:2005Natur.437.1173R. doi:10.1038/nature04209. PMID 16189514. S2CID 4427026.
Oh JH, Yang JO, Hahn Y, Kim MR, Byun SS, Jeon YJ, Kim JM, Song KS, Noh SM, Kim S, Yoo HS, Kim YS, Kim NS (2006). "Transcriptome analysis of human gastric cancer". Mamm. Genome. 16 (12): 942–54. doi:10.1007/s00335-005-0075-2. PMID 16341674. S2CID 69278.

[refGRCh38Ensembl-1] GRCh38: Ensembl release 89: ENSG00000132603 – Ensembl, May 2017

[refGRCm38Ensembl-2] GRCm38: Ensembl release 89: ENSMUSG00000031917 – Ensembl, May 2017

[3] "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[4] "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[pmid14660641-5] Sekiguchi T, Todaka Y, Wang Y, Hirose E, Nakashima N, Nishimoto T (Feb 2004). "A novel human nucleolar protein, Nop132, binds to the G proteins, RRAG A/C/D". J Biol Chem. 279 (9): 8343–50. doi:10.1074/jbc.M305935200. PMID 14660641.

[entrez-6] "Entrez Gene: NIP7 nuclear import 7 homolog (S. cerevisiae)".

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