Article · Wikipedia archive · Last revised Jun 17, 2026

Neointima

Neointima typically refers to scar tissue that forms within tubular anatomical structures such as blood vessels, as the intima is the innermost lining of these structures. Neointima can form as a result of vascular surgery such as angioplasty or stent placement. Formation of neointima occurs due to proliferation of smooth muscle cells as well as macrophages.

Last revised
Jun 17, 2026
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Neointima typically refers to scar tissue that forms within tubular anatomical structures such as blood vessels, as the intima is the innermost lining of these structures. Neointima can form as a result of vascular surgery such as angioplasty or stent placement.1 Formation of neointima occurs due to proliferation of smooth muscle cells2 as well as macrophages. 1

References

References

  1. Komatsu, Ryushi; Ueda, Makiko; Naruko, Takahiko; Kojima, Akiko; Becker, Anton E. (21 July 1998). "Neointimal Tissue Response at Sites of Coronary Stenting in Humans: Macroscopic, Histological, and Immunohistochemical Analyses". Circulation. 98 (3): 224–233. doi:10.1161/01.CIR.98.3.224. ISSN 0009-7322.
  2. Hoglund, Virginia J.; Dong, Xiu Rong; Majesky, Mark W. (October 2010). "Neointima Formation: A Local Affair". Arteriosclerosis, Thrombosis, and Vascular Biology. 30 (10): 1877–1879. doi:10.1161/ATVBAHA.110.211433. ISSN 1079-5642. PMC 3049730.