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Mouse ear swelling test

The mouse ear swelling test is a toxicological test that aims to mimic human skin reactions to chemicals. It avoids post-mortem examination of tested animals.

Last revised
Jul 3, 2026
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≈ 1 min
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The mouse ear swelling test is a toxicological test that aims to mimic human skin reactions to chemicals.1 It avoids post-mortem examination of tested animals.2

References

References

  1. Gad, S. C. (1994-09-22). "The mouse ear swelling test (MEST) in the 1990s". Toxicology. 93 (1): 33–46. Bibcode:1994Toxgy..93...33G. doi:10.1016/0300-483x(94)90194-5. PMID 7974503.
  2. Gad SC; Dunn BJ; Dobbs DW; Reilly C; Walsh RD (1986), "Development and validation of an alternative dermal sensitization test: the mouse ear swelling test (MEST)", Toxicology and Applied Pharmacology, 86 (1): 93–114, Bibcode:1986ToxAP..84...93G, doi:10.1016/0041-008x(86)90419-9, PMID 3715870
See also

See also