Article · Wikipedia archive · Last revised Jun 27, 2026

MMDA-3a

MMDA-3a, also known as 2-methoxy-3,4-methylenedioxyamphetamine or as 2-methoxy-MDA, is a psychedelic drug of the amphetamine family. It is the 2-methoxy derivative of 3,4-methylenedioxyamphetamine (MDA). The drug produces hallucinogenic effects in humans. Its dose is listed as 20 to 80 mg orally and its duration as 10 to 16 hours in Alexander Shulgin's book PiHKAL. A higher dose of 100 mg was also reportedly explored and doses of 80 to 100 mg were said to be very similar to 100 μg LSD. The chemical synthesis of MMDA-3a has been described. MMDA-3a is a positional isomer of MMDA and hence is a Schedule I controlled substance in the United States. It is also a controlled substance in Canada under phenethylamine blanket-ban language.

Last revised
Jun 27, 2026
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MMDA-3a
Clinical data
Other names2-Methoxy-3,4-methylenedioxyamphetamine; 2-Methoxy-MDA; 2-MeO-MDA
Routes of
administration		Oral12
Drug classSerotonergic psychedelic; Hallucinogen
ATC code
  • None
Pharmacokinetic data
Duration of action10–16 hours12
Identifiers
  • 1-(4-methoxy-1,3-benzodioxol-5-yl)propan-2-amine
CAS Number
PubChem CID
ChemSpider
UNII
ChEMBL
CompTox Dashboard (EPA)
Chemical and physical data
FormulaC11H15NO3
Molar mass209.245 g·mol−1
3D model (JSmol)
  • CC(CC1=C(C2=C(C=C1)OCO2)OC)N
  • InChI=1S/C11H15NO3/c1-7(12)5-8-3-4-9-11(10(8)13-2)15-6-14-9/h3-4,7H,5-6,12H2,1-2H3
  • Key:OSJXZWMDUMAITM-UHFFFAOYSA-N

MMDA-3a, also known as 2-methoxy-3,4-methylenedioxyamphetamine or as 2-methoxy-MDA, is a psychedelic drug of the amphetamine family.12 It is the 2-methoxy derivative of 3,4-methylenedioxyamphetamine (MDA).1 The drug produces hallucinogenic effects in humans.1 Its dose is listed as 20 to 80 mg orally and its duration as 10 to 16 hours in Alexander Shulgin's book PiHKAL (Phenethylamines I Have Known and Loved).12 A higher dose of 100 mg was also reportedly explored and doses of 80 to 100 mg were said to be very similar to 100 μg LSD.1 The chemical synthesis of MMDA-3a has been described.12 MMDA-3a is a positional isomer of MMDA and hence is a Schedule I controlled substance in the United States.2 It is also a controlled substance in Canada under phenethylamine blanket-ban language.3

See also

See also

References

References

  1. Alexander T. Shulgin; Ann Shulgin (1991). "#134 MMDA-3a 2-METHOXY-3,4-METHYLENEDIOXYAMPHETAMINE". PiHKAL: A Chemical Love Story (1st ed.). Berkeley, CA: Transform Press. pp. 795–798. ISBN 978-0-9630096-0-9. OCLC 25627628.
  2. Shulgin A, Manning T, Daley PF (2011). "#99. MMDA-3a". The Shulgin Index, Volume One: Psychedelic Phenethylamines and Related Compounds. Vol. 1. Berkeley, CA: Transform Press. pp. 240–241. ISBN 978-0-9630096-3-0. OCLC 709667010.
  3. "Controlled Drugs and Substances Act". Department of Justice Canada. Retrieved 19 January 2026.
External links