Article · Wikipedia archive · Last revised Jun 22, 2026

MIER1

Mesoderm induction early response protein 1 is a protein that in humans is encoded by the MIER1 gene.

Last revised
Jun 22, 2026
Read time
≈ 3 min
Length
695 w
Citations
12
Source
MIER1
Identifiers
AliasesMIER1, ER1, MI-ER1, MIER1 transcriptional regulator
External IDsOMIM: 616848; MGI: 1918398; HomoloGene: 136176; GeneCards: MIER1; OMA:MIER1 - orthologs
Orthologs
SpeciesHumanMouse
Entrez
Ensembl
UniProt
RefSeq (mRNA)

NM_001039081
NM_001286221
NM_001286222
NM_001286223
NM_027696

RefSeq (protein)
Location (UCSC)Chr 1: 66.92 – 66.99 MbChr 4: 102.97 – 103.02 Mb
PubMed search34
Wikidata
View/Edit HumanView/Edit Mouse

Mesoderm induction early response protein 1 is a protein that in humans is encoded by the MIER1 gene.567

Interactions

MIER1 has been shown to interact with HDAC1.6

References

References

  1. GRCh38: Ensembl release 89: ENSG00000198160Ensembl, May 2017
  2. GRCm38: Ensembl release 89: ENSMUSG00000028522Ensembl, May 2017
  3. "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  4. "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  5. Paterno GD, Ding Z, Lew YY, Nash GW, Mercer FC, Gillespie LL (Jul 2002). "Genomic organization of the human mi-er1 gene and characterization of alternatively spliced isoforms: regulated use of a facultative intron determines subcellular localization". Gene. 295 (1): 79–88. doi:10.1016/S0378-1119(02)00823-5. PMID 12242014.
  6. Ding Z, Gillespie LL, Paterno GD (Jan 2003). "Human MI-ER1 alpha and beta function as transcriptional repressors by recruitment of histone deacetylase 1 to their conserved ELM2 domain". Molecular and Cellular Biology. 23 (1): 250–8. doi:10.1128/MCB.23.1.250-258.2003. PMC 140656. PMID 12482978.
  7. "Entrez Gene: MIER1 mesoderm induction early response 1 homolog (Xenopus laevis)".
Further reading

Further reading