Article · Wikipedia archive · Last revised Jun 1, 2026

Methylpropyltryptamine

Methylpropyltryptamine (MPT), also known as N-methyl-N-propyltryptamine, is a psychedelic drug of the tryptamine family. It is a homologue of methylethyltryptamine (MET).

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Jun 1, 2026
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Methylpropyltryptamine
Clinical data
Other namesMPT; N-Methyl-N-propyltryptamine
Routes of
administration		Oral1
Drug classSerotonergic psychedelic; Hallucinogen
ATC code
  • None
Identifiers
  • N-[2-(1H-indol-3-yl)ethyl]-N-methylpropan-1-amine
CAS Number
PubChem CID
ChemSpider
UNII
Chemical and physical data
FormulaC14H20N2
Molar mass216.328 g·mol−1
3D model (JSmol)
  • CCCN(C)CCC1=CNC2=C1C=CC=C2
  • InChI=1S/C14H20N2/c1-3-9-16(2)10-8-12-11-15-14-7-5-4-6-13(12)14/h4-7,11,15H,3,8-10H2,1-2H3
  • Key:SZUNESAKJQIJAC-UHFFFAOYSA-N

Methylpropyltryptamine (MPT), also known as N-methyl-N-propyltryptamine, is a psychedelic drug of the tryptamine family. It is a homologue of methylethyltryptamine (MET).1

Use and effects

In his book TiHKAL (Tryptamines I Have Known and Loved), Alexander Shulgin described MPT's effects as being unknown and its dose as being greater than 50 mg orally.1

Interactions

Chemistry

Detection

An analytical method for MPT's detection has been reported.2

Crystal structure

In 2019, Chadeayne et al. published the crystal structure of MPT.3 The authors describe the structure as "...a single molecule in the asymmetric unit, with an indole group that demonstrates a mean deviation from planarity of 0.015 A°."

Analogues

Analogues of MPT include 4-HO-MPT, 5-MeO-MPT, methylethyltryptamine (MET), ethylpropyltryptamine (EPT), ethylisopropyltryptamine (EiPT), and dipropyltryptamine (DPT), among others.1

Society and culture

Canada

MPT is not a controlled substance in Canada as of 2025.4

United States

MPT is not an explicitly controlled substance in the United States.5 However, it is an isomer of diethyltryptamine (DET), which is a schedule I controlled substance in this country, and so may be considered a controlled substance in the United States similarly.56

See also

See also

References

References

  1. Shulgin A, Shulgin A (September 1997). TiHKAL: The Continuation. Berkeley, California: Transform Press. ISBN 0-9630096-9-9. OCLC 38503252.
  2. Brandt SD, Freeman S, Fleet IA, Alder JF (September 2005). "Analytical chemistry of synthetic routes to psychoactive tryptamines. Part III. Characterisation of the Speeter and Anthony route to N,N-dialkylated tryptamines using CI-IT-MS-MS". The Analyst. 130 (9): 1258–1262. Bibcode:2005Ana...130.1258B. doi:10.1039/b504001a. PMID 16096671.
  3. Chadeayne AR, Golen JA, Manke DR (2019-07-28). "N -Methyl- N -propyltryptamine (MPT)". IUCrData. 4 (7) x190962. Bibcode:2019IUCrD...490962C. doi:10.1107/S2414314619009623. ISSN 2414-3146.
  4. "Controlled Drugs and Substances Act". Department of Justice Canada. Retrieved 19 January 2026.
  5. Orange Book: List of Controlled Substances and Regulated Chemicals (January 2026) (PDF), United States: U.S. Department of Justice: Drug Enforcement Administration (DEA): Diversion Control Division, January 2026
  6. Drug Enforcement Administration (3 December 2007). "Definition of "Positional Isomer" as It Pertains to the Control of Schedule I Controlled Substances". Federal Register.
External links