Article · Wikipedia archive · Last revised Jul 6, 2026

Methoxpropamine

Methoxpropamine is a dissociative anesthetic drug of the arylcyclohexylamine class and NMDA receptor antagonist that is closely related to substances such as methoxetamine and PCPr. It has been sold online as a designer drug, first being identified in Denmark in October 2019, and is illegal in Finland.

Last revised
Jul 6, 2026
Read time
≈ 1 min
Length
228 w
Citations
4
Source
Wikipedia ↗
Methoxpropamine
Legal status
Legal status
Identifiers
  • 2-(3-Methoxyphenyl)-2-(propylamino)cyclohexanone
CAS Number
PubChem CID
ChemSpider
UNII
CompTox Dashboard (EPA)
Chemical and physical data
FormulaC16H23NO2
Molar mass261.365 g·mol−1
3D model (JSmol)
  • COc1cccc(c1)C2(NCCC)CCCCC2=O
  • InChI=1S/C16H23NO2/c1-3-11-17-16(10-5-4-9-15(16)18)13-7-6-8-14(12-13)19-2/h6-8,12,17H,3-5,9-11H2,1-2H3
  • Key:AAVOSBAXDRASAH-UHFFFAOYSA-N

Methoxpropamine (MXPr, 2-Oxo-3'-methoxy-PCPr) is a dissociative anesthetic drug of the arylcyclohexylamine class and NMDA receptor antagonist1 that is closely related to substances such as methoxetamine and PCPr.2 It has been sold online as a designer drug, first being identified in Denmark in October 2019,3 and is illegal in Finland.4

See also

See also

References

References

  1. Irie T, Yamazaki D, Kikura-Hanajiri R (July 2021). "A potential of methoxpropamine to be a widespread recreational drug: it blocks NMDA receptors and inhibits NMDA receptor-mediated synaptic transmission in a brain preparation of mice". Forensic Toxicology. 39 (2): 474–80. doi:10.1007/s11419-021-00571-0. S2CID 232273277.
  2. Goncalves R, Castaing N, Richeval C, Ducint D, Titier K, Morvan E, et al. (April 2022). "Methoxpropamine (MXPr) in powder, urine and hair samples: Analytical characterization and metabolite identification of a new threat". Forensic Science International. 333 111215. doi:10.1016/j.forsciint.2022.111215. PMID 35151938. S2CID 246685658.
  3. "EU Early Warning System Situation Report. Situation report 1" (PDF). European Monitoring Centre for Drugs and Drug Addiction (EMCDDA). June 2020.
  4. "Valtioneuvoston asetus kuluttajamarkkinoilta kielletyistä psykoaktiivisista aineista" [Government decree on psychoactive substances banned from the consumer market]. Finlex Data Bank (in Finnish). Finnish Ministry of Justice.