Mebhydrolin

Mebhydrolin
Clinical data
Other names	9-Benzyl-2-methyl-2,3,4,9-tetrahydro-1H-gamma-carboline, Incidal, Omeril, Diazolin, Fabahistin, mebhydrolin napadisylate, mebhydroline 1,5-naphthalenedisulfonate
AHFS/Drugs.com	International Drug Names
Pregnancy; category	Not established;
Routes of; administration	Oral
ATC code	R06AX15 (WHO) ;
Legal status
Legal status	In general: ℞ (Prescription only);
Identifiers
	IUPAC name 5-benzyl-2-methyl-3,4-dihydro-1H-pyrido[4,3-b]indole;
CAS Number	524-81-2 Y ; 6153-33-9 (1,5-naphthalenedisulfonate salt);
PubChem CID	22530;
ChemSpider	21129 Y;
UNII	9SUK9B7XVY;
KEGG	D08161 Y;
CompTox Dashboard (EPA)	DTXSID5048558 ;
ECHA InfoCard	100.007.606
Chemical and physical data
Formula	C19H20N2
Molar mass	276.383 g·mol−1
3D model (JSmol)	Interactive image;
	SMILES CN3Cc4c1ccccc1n(Cc2ccccc2)c4CC3;
	InChI InChI=1S/C19H20N2/c1-20-12-11-19-17(14-20)16-9-5-6-10-18(16)21(19)13-15-7-3-2-4-8-15/h2-10H,11-14H2,1H3 Y; Key:FQQIIPAOSKSOJM-UHFFFAOYSA-N Y;
	NY (what is this?) (verify)

Mebhydrolin (INN) or mebhydroline is an antihistamine. It is not available in the United States, but it is in various other countries under the brand names Bexidal (BD) and Diazolin (RU). It is used for symptomatic relief of allergic symptoms caused by histamine release, including nasal allergies and allergic dermatosis.

Mebhydrolin has been shown to magnify the performance-deficit effects of alcohol.⁵

References

"Mebhydroline". National Library of Medicine - Medical Subject Headings. US National Institutes of Health, National Library of Medicine. Retrieved 2007-03-02.
"FABAHISTIN 50 mg (Tablets)". South African Electronic Package Inserts. September 1970. Archived from the original on October 17, 2006. Retrieved 2007-03-02.
"Diazoline". National Library of Medicine - Medical Subject Headings. US National Institutes of Health, National Library of Medicine. Archived from the original on January 19, 2016. Retrieved 2007-03-02.
"Mebhydrolin chemical information". PubChem. Retrieved 2007-03-02.
Franks HM, Lawrie M, Schabinsky VV, Starmer GA, Teo RK (October 1981). "Interaction between ethanol and antihistamines: 3. mebhydrolin". Med. J. Aust. 2 (9): 477–9. doi:10.5694/j.1326-5377.1981.tb112944.x. PMID 6119605. S2CID 11034501.

[MeSH_mebhydroline-1] "Mebhydroline". National Library of Medicine - Medical Subject Headings. US National Institutes of Health, National Library of Medicine. Retrieved 2007-03-02.

[Intekom-2] "FABAHISTIN 50 mg (Tablets)". South African Electronic Package Inserts. September 1970. Archived from the original on October 17, 2006. Retrieved 2007-03-02.

[MeSH_diazoline-3] "Diazoline". National Library of Medicine - Medical Subject Headings. US National Institutes of Health, National Library of Medicine. Archived from the original on January 19, 2016. Retrieved 2007-03-02.

[ChemIndustry-4] "Mebhydrolin chemical information". PubChem. Retrieved 2007-03-02.

[5] Franks HM, Lawrie M, Schabinsky VV, Starmer GA, Teo RK (October 1981). "Interaction between ethanol and antihistamines: 3. mebhydrolin". Med. J. Aust. 2 (9): 477–9. doi:10.5694/j.1326-5377.1981.tb112944.x. PMID 6119605. S2CID 11034501.

1

2

3

4

5