MAP kinase kinase kinase kinase

Mitogen-activated protein kinase kinase kinase kinase (MAP4K) is a family of proteins involved in cellular signal transduction.

• MAP4K1 (aka HPK1)
• MAP4K2 (aka GCK)
• MAP4K3 (aka GLK)
• MAP4K4 (aka HGK)
• MAP4K5 (aka KHS)
• MAP4K6 (aka MINK)

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  Some signal transduction pathways. MAP4K is not labelled.
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  MAPK pathway. Some (or all) of the MAP4Ks in this image are labelled by other names, such as HPK1 and GCK.