MAGEH1

MAGEH1
Identifiers
Aliases	MAGEH1, APR-1, APR1, MAGEH, MAGE family member H1
External IDs	OMIM: 300548; MGI: 1922875; HomoloGene: 8545; GeneCards: MAGEH1; OMA:MAGEH1 - orthologs
Gene location (Human)
Chr.	X chromosome (human)
End	55,453,566 bp
Gene location (Mouse)
Chr.	X chromosome (mouse)
End	151,820,571 bp
RNA expression pattern
	Top expressed in
	corpus epididymis; ; endothelial cell; ; pons; ; Brodmann area 9; ; hypothalamus; ; superior vestibular nucleus; ; cerebellar vermis; ; tibia; ; anterior pituitary; ; prefrontal cortex;
	Top expressed in
	median eminence; ; superior cervical ganglion; ; arcuate nucleus; ; islet of Langerhans; ; paraventricular nucleus of hypothalamus; ; mammillary body; ; medial ganglionic eminence; ; lateral septal nucleus; ; medial vestibular nucleus; ; dorsomedial hypothalamic nucleus;
	More reference expression data
	More reference expression data
Gene ontology
Molecular function	protein binding;
Cellular component	cytoplasm;
Biological process	apoptotic process;
	Sources:Amigo / QuickGO
Orthologs
	28986
	75625
	ENSG00000187601
	ENSMUSG00000047238
	Q9H213
	Q9NWG9
	NM_014061
	NM_023788
	NP_054780
	NP_076277
	Wikidata
View/Edit Human	View/Edit Mouse

Melanoma-associated antigen H1 is a protein that in humans is encoded by the MAGEH1 gene.⁵⁶⁷

This gene is thought to be involved in apoptosis. Multiple polyadenylation sites have been found for this gene.⁷

Interactions

MAGEH1 has been shown to interact with Low affinity nerve growth factor receptor.⁵

References

GRCh38: Ensembl release 89: ENSG00000187601 – Ensembl, May 2017
GRCm38: Ensembl release 89: ENSMUSG00000047238 – Ensembl, May 2017
"Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
"Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
Tcherpakov M, Bronfman FC, Conticello SG, Vaskovsky A, Levy Z, Niinobe M, Yoshikawa K, Arenas E, Fainzilber M (Dec 2002). "The p75 neurotrophin receptor interacts with multiple MAGE proteins". J Biol Chem. 277 (51): 49101–4. doi:10.1074/jbc.C200533200. PMID 12414813.
Lucas S, De Smet C, Arden KC, Viars CS, Lethe B, Lurquin C, Boon T (Mar 1998). "Identification of a new MAGE gene with tumor-specific expression by representational difference analysis". Cancer Res. 58 (4): 743–52. PMID 9485030.
"Entrez Gene: MAGEH1 melanoma antigen family H, 1".

Further reading

Zhu F, Yan W, Zhao ZL, et al. (2001). "Improved PCR-based subtractive hybridization strategy for cloning differentially expressed genes". BioTechniques. 29 (2): 310–3. doi:10.2144/00292st06. PMID 10948432.
Chomez P, De Backer O, Bertrand M, et al. (2001). "An overview of the MAGE gene family with the identification of all human members of the family". Cancer Res. 61 (14): 5544–51. PMID 11454705.
Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. Bibcode:2002PNAS...9916899M. doi:10.1073/pnas.242603899. PMC 139241. PMID 12477932.
Goehler H, Lalowski M, Stelzl U, et al. (2004). "A protein interaction network links GIT1, an enhancer of huntingtin aggregation, to Huntington's disease". Mol. Cell. 15 (6): 853–65. doi:10.1016/j.molcel.2004.09.016. PMID 15383276.
Gerhard DS, Wagner L, Feingold EA, et al. (2004). "The Status, Quality, and Expansion of the NIH Full-Length cDNA Project: The Mammalian Gene Collection (MGC)". Genome Res. 14 (10B): 2121–7. doi:10.1101/gr.2596504. PMC 528928. PMID 15489334.
Ross MT, Grafham DV, Coffey AJ, et al. (2005). "The DNA sequence of the human X chromosome". Nature. 434 (7031): 325–37. Bibcode:2005Natur.434..325R. doi:10.1038/nature03440. PMC 2665286. PMID 15772651.
Rual JF, Venkatesan K, Hao T, et al. (2005). "Towards a proteome-scale map of the human protein-protein interaction network". Nature. 437 (7062): 1173–8. Bibcode:2005Natur.437.1173R. doi:10.1038/nature04209. PMID 16189514. S2CID 4427026.
Fu H, Yang G, Lu F, et al. (2006). "Transcriptional up-regulation of restin by all-trans retinoic acid through STAT1 in cancer cell differentiation process". Biochem. Biophys. Res. Commun. 343 (4): 1009–16. Bibcode:2006BBRC..343.1009F. doi:10.1016/j.bbrc.2006.02.176. PMID 16574066.

[refGRCh38Ensembl-1] GRCh38: Ensembl release 89: ENSG00000187601 – Ensembl, May 2017

[refGRCm38Ensembl-2] GRCm38: Ensembl release 89: ENSMUSG00000047238 – Ensembl, May 2017

[3] "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[4] "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[pmid12414813-5] Tcherpakov M, Bronfman FC, Conticello SG, Vaskovsky A, Levy Z, Niinobe M, Yoshikawa K, Arenas E, Fainzilber M (Dec 2002). "The p75 neurotrophin receptor interacts with multiple MAGE proteins". J Biol Chem. 277 (51): 49101–4. doi:10.1074/jbc.C200533200. PMID 12414813.

[pmid9485030-6] Lucas S, De Smet C, Arden KC, Viars CS, Lethe B, Lurquin C, Boon T (Mar 1998). "Identification of a new MAGE gene with tumor-specific expression by representational difference analysis". Cancer Res. 58 (4): 743–52. PMID 9485030.

[entrez-7] "Entrez Gene: MAGEH1 melanoma antigen family H, 1".

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