Article · Wikipedia archive · Last revised Jul 6, 2026

M-ALPHA

M-ALPHA, also known as 3,4-methylenedioxy-α-ethyl-N-methylbenzylamine or as α-ethyl-N-methylpiperonylamine, is a psychoactive drug of the substituted benzylamine group. It was reported by Alexander Shulgin in his book PIHKAL as a positional isomer of MDMA. Subsequently, the drug was encountered as a designer drug in the United Kingdom in 2010 and was reported to the EMCDDA new drug monitoring service. It was described by Shulgin as similar in action to its demethylated homologue, ALPHA, but with roughly twice the duration and twice the potency. ALPHA itself was described as active at doses of 10 to 140 mg, with a duration of about 3 hours, and producing eyes-closed "dreams", some body tingling, and a pleasant positive feeling, but without any appetite suppression. M-ALPHA was encountered as a designer drug by 2010.

Last revised
Jul 6, 2026
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M-ALPHA
Clinical data
Other names3,4-Methylenedioxy-α-ethyl-N-methylbenzylamine; α-Ethyl-N-methylpiperonylamine; 1-Methylamino-1-(3,4-methylenedioxyphenyl)propane
Routes of
administration		Oral1
Drug classUnknown1
ATC code
  • None
Pharmacokinetic data
Duration of action~6 hours1
Identifiers
  • 1-(1,3-Benzodioxol-5-yl)-N-methylpropan-1-amine
CAS Number
PubChem CID
ChemSpider
UNII
CompTox Dashboard (EPA)
Chemical and physical data
FormulaC11H15NO2
Molar mass193.246 g·mol−1
3D model (JSmol)
  • CNC(CC)C1=CC2=C(C=C1)OCO2
  • InChI=1S/C11H15NO2/c1-3-9(12-2)8-4-5-10-11(6-8)14-7-13-10/h4-6,9,12H,3,7H2,1-2H3 ☒N
  • Key:NLINVDHEDVEOMJ-UHFFFAOYSA-N ☒N
  (verify)

M-ALPHA, also known as 3,4-methylenedioxy-α-ethyl-N-methylbenzylamine or as α-ethyl-N-methylpiperonylamine, is a psychoactive drug of the substituted benzylamine group.12 It was reported by Alexander Shulgin in his book PIHKAL as a positional isomer of MDMA.12 Subsequently, the drug was encountered as a designer drug in the United Kingdom in 2010 and was reported to the EMCDDA new drug monitoring service.3 It was described by Shulgin as similar in action to its demethylated homologue, ALPHA, but with roughly twice the duration and twice the potency.1 ALPHA itself was described as active at doses of 10 to 140 mg, with a duration of about 3 hours, and producing eyes-closed "dreams", some body tingling, and a pleasant positive feeling, but without any appetite suppression.1 M-ALPHA was encountered as a designer drug by 2010.4

See also

See also

References

References

  1. Shulgin A, Shulgin A (September 1991). PiHKAL: A Chemical Love Story. Berkeley, California: Transform Press. ISBN 0-9630096-0-5. OCLC 25627628.
  2. Shulgin A, Manning T, Daley PF (2011). The Shulgin Index, Volume One: Psychedelic Phenethylamines and Related Compounds. Vol. 1. Berkeley: Transform Press. ISBN 978-0-9630096-3-0.
  3. "EMCDDA Annual Report 2010" (PDF). Archived from the original (PDF) on 2012-03-14. Retrieved 2011-10-10.
  4. "EMCDDA–Europol 2010 Annual Report on the implementation of Council Decision 2005/387/JHA". www.euda.europa.eu. 2 July 2024. Retrieved 9 April 2025.
External links