LRRC3B

LRRC3B
Identifiers
Aliases	LRRC3B, LRP15, leucine rich repeat containing 3B
External IDs	MGI: 2384996; HomoloGene: 14190; GeneCards: LRRC3B; OMA:LRRC3B - orthologs
Gene location (Human)
Chr.	Chromosome 3 (human)
End	26,717,537 bp
Gene location (Mouse)
Chr.	Chromosome 14 (mouse)
End	7,112,248 bp
RNA expression pattern
	Top expressed in
	ventricular zone; ; ganglionic eminence; ; secondary oocyte; ; cerebellum; ; cerebellar cortex; ; cerebellar hemisphere; ; right hemisphere of cerebellum; ; amygdala; ; pars reticulata; ; pars compacta;
	Top expressed in
	habenula; ; right ventricle; ; cardiac muscles; ; olfactory epithelium; ; lobe of cerebellum; ; interventricular septum; ; ventral tegmental area; ; cerebellar vermis; ; extraocular muscle; ; myocardium of ventricle;
	More reference expression data
	n/a
Orthologs
	116135
	218763
	ENSG00000179796
	ENSMUSG00000045201
	Q96PB8
	Q8VCH9
NM_052953; NM_001317808; NM_001317809; NM_001317810; NM_001317811;
	NM_001395645; NM_001395646; NM_001395647
	NM_146052
	NP_001304737; NP_001304738; NP_001304739; NP_001304740; NP_443185
	NP_666164
	Wikidata
View/Edit Human	View/Edit Mouse

LRRC3B is a gene frequently epigenetically inactivated in several epithelial malignancies and inhibits cell growth and replication. Data suggest that the LRRC3B gene could be involved in the process of carcinogenesis as a tumor suppressor gene.⁵

References

GRCh38: Ensembl release 89: ENSG00000179796 – Ensembl, May 2017
GRCm38: Ensembl release 89: ENSMUSG00000045201 – Ensembl, May 2017
"Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
"Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
Haraldson K, Kashuba VI, Dmitriev AA, Senchenko VN, Kudryavtseva AV, Pavlova TV, Braga EA, Pronina IV, Kondratov AG, Rynditch AV, Lerman MI, Zabarovsky ER (2012). "LRRC3B is a gene frequently epigenetically inactivated in several epithelial malignancies and inhibits cell growth and replication". Biochimie. 94 (9): 1151–1157. doi:10.1016/j.biochi.2012.01.019. PMID 22321817.

[refGRCh38Ensembl-1] GRCh38: Ensembl release 89: ENSG00000179796 – Ensembl, May 2017

[refGRCm38Ensembl-2] GRCm38: Ensembl release 89: ENSMUSG00000045201 – Ensembl, May 2017

[3] "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[4] "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[5] Haraldson K, Kashuba VI, Dmitriev AA, Senchenko VN, Kudryavtseva AV, Pavlova TV, Braga EA, Pronina IV, Kondratov AG, Rynditch AV, Lerman MI, Zabarovsky ER (2012). "LRRC3B is a gene frequently epigenetically inactivated in several epithelial malignancies and inhibits cell growth and replication". Biochimie. 94 (9): 1151–1157. doi:10.1016/j.biochi.2012.01.019. PMID 22321817.

1

2

3

4

5