KCNH4

KCNH4
Identifiers
Aliases	KCNH4, BEC2, ELK1, Kv12.3, potassium voltage-gated channel subfamily H member 4
External IDs	OMIM: 604528; MGI: 2156184; HomoloGene: 8180; GeneCards: KCNH4; OMA:KCNH4 - orthologs
Gene location (Human)
Chr.	Chromosome 17 (human)
End	42,181,142 bp
Gene location (Mouse)
Chr.	Chromosome 11 (mouse)
End	100,650,768 bp
RNA expression pattern
	Top expressed in
	putamen; ; testicle; ; caudate nucleus; ; nucleus accumbens; ; prefrontal cortex; ; right frontal lobe; ; Brodmann area 9; ; primary visual cortex; ; anterior cingulate cortex; ; appendix;
	Top expressed in
	striatum of neuraxis; ; superior frontal gyrus; ; primary visual cortex; ; mesencephalon; ; olfactory bulb; ; neural tube; ; epiblast; ; ganglionic eminence; ; hypothalamus; ; rhombencephalon;
	More reference expression data
	n/a
Gene ontology
Molecular function	voltage-gated ion channel activity; ion channel activity; phosphorelay sensor kinase activity; potassium channel activity; voltage-gated potassium channel activity;
Cellular component	integral component of membrane; intracellular anatomical structure; plasma membrane; voltage-gated potassium channel complex; membrane; integral component of plasma membrane;
Biological process	ion transport; phosphorelay signal transduction system; signal transduction; potassium ion transmembrane transport; potassium ion transport; regulation of ion transmembrane transport; transmembrane transport; regulation of membrane potential;
	Sources:Amigo / QuickGO
Orthologs
	23415
	380728
	ENSG00000089558
	ENSMUSG00000035355
	Q9UQ05
	A2A5F7
	NM_012285
	NM_001081194
	NP_036417
	NP_001074663
	Wikidata
View/Edit Human	View/Edit Mouse

Potassium voltage-gated channel subfamily H member 4 is a protein, that in humans, is encoded by the KCNH4 gene.⁵⁶ The protein encoded by this gene is a voltage-gated potassium channel subunit.⁵⁶

References

GRCh38: Ensembl release 89: ENSG00000089558 – Ensembl, May 2017
GRCm38: Ensembl release 89: ENSMUSG00000035355 – Ensembl, May 2017
"Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
"Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
Miyake A, Mochizuki S, Yokoi H, Kohda M, Furuichi K (Sep 1999). "New ether-a-go-go K(+) channel family members localized in human telencephalon". J Biol Chem. 274 (35): 25018–25. doi:10.1074/jbc.274.35.25018. PMID 10455180.
Gutman GA, Chandy KG, Grissmer S, Lazdunski M, McKinnon D, Pardo LA, Robertson GA, Rudy B, Sanguinetti MC, Stuhmer W, Wang X (Dec 2005). "International Union of Pharmacology. LIII. Nomenclature and molecular relationships of voltage-gated potassium channels". Pharmacol Rev. 57 (4): 473–508. doi:10.1124/pr.57.4.10. PMID 16382104. S2CID 219195192.

External links

Kv12.3+Potassium+Channel at the U.S. National Library of Medicine Medical Subject Headings (MeSH)
KCNH4+protein,+human at the U.S. National Library of Medicine Medical Subject Headings (MeSH)

[refGRCh38Ensembl-1] GRCh38: Ensembl release 89: ENSG00000089558 – Ensembl, May 2017

[refGRCm38Ensembl-2] GRCm38: Ensembl release 89: ENSMUSG00000035355 – Ensembl, May 2017

[3] "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[4] "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[pmid10455180-5] Miyake A, Mochizuki S, Yokoi H, Kohda M, Furuichi K (Sep 1999). "New ether-a-go-go K(+) channel family members localized in human telencephalon". J Biol Chem. 274 (35): 25018–25. doi:10.1074/jbc.274.35.25018. PMID 10455180.

[pmid16382104-6] Gutman GA, Chandy KG, Grissmer S, Lazdunski M, McKinnon D, Pardo LA, Robertson GA, Rudy B, Sanguinetti MC, Stuhmer W, Wang X (Dec 2005). "International Union of Pharmacology. LIII. Nomenclature and molecular relationships of voltage-gated potassium channels". Pharmacol Rev. 57 (4): 473–508. doi:10.1124/pr.57.4.10. PMID 16382104. S2CID 219195192.

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