Article · Wikipedia archive · Last revised Jun 19, 2026

Ioxilan

Ioxilan is a diagnostic contrast agent. It is injected intravenously before taking X-ray images to increase arterial contrast in the final image. It was marketed in the US under the trade name Oxilan by Guerbet, L.L.C., but was discontinued in 2017.

Last revised
Jun 19, 2026
Read time
≈ 1 min
Length
137 w
Citations
3
Source
Wikipedia ↗
Ioxilan
Clinical data
Trade namesOxilan
AHFS/Drugs.comFDA Professional Drug Information
Routes of
administration		intravenously
ATC code
Legal status
Legal status
Pharmacokinetic data
BioavailabilityN/A
Protein bindingnegligible
Metabolismnone
Elimination half-life2 hours
ExcretionMostly renal
Identifiers
  • 1-N-(2,3-dihydroxypropyl)-5-[N-(2,3-dihydroxypropyl)acetamido]-3-N-(2-hydroxyethyl)-2,4,6-triiodobenzene-1,3-dicarboxamide
CAS Number
PubChem CID
DrugBank
ChemSpider
UNII
KEGG
ChEMBL
CompTox Dashboard (EPA)
Chemical and physical data
FormulaC18H24I3N3O8
Molar mass791.116 g·mol−1
3D model (JSmol)
  • O=C(N(c1c(I)c(c(I)c(c1I)C(=O)NCCO)C(=O)NCC(O)CO)CC(O)CO)C
  • InChI=1S/C18H24I3N3O8/c1-8(28)24(5-10(30)7-27)16-14(20)11(17(31)22-2-3-25)13(19)12(15(16)21)18(32)23-4-9(29)6-26/h9-10,25-27,29-30H,2-7H2,1H3,(H,22,31)(H,23,32) checkY
  • Key:UUMLTINZBQPNGF-UHFFFAOYSA-N checkY
 ☒NcheckY (what is this?)  (verify)

Ioxilan is a diagnostic contrast agent.1 It is injected intravenously before taking X-ray images to increase arterial contrast in the final image. It was marketed in the US under the trade name Oxilan by Guerbet, L.L.C., but was discontinued in 2017.2

Mechanism of action

Ioxilan is an iodinated contrast agent.2

References

References

  1. Cheng KT (December 2007). "Ioxilan carbonate particles". Molecular Imaging and Contrast Agent Database (MICAD) [Internet]. Bethesda (MD): National Center for Biotechnology Information (US). PMID 20641969.
  2. Oxilan FDA Professional Drug Information. Accessed 2021-04-07.