Inparanoid is an algorithm that finds orthologous genes and paralogous genes that arose—most likely by duplication—after some speciation event. Such protein-coding genes are called in-paralogs, as opposed to out-paralogs (which arose prior to a species split).1
Inparanoid (with varying capitalization) may refer to a program that uses the INPARANOID algorithm, or to the derived database of orthologous clusters of genes.2
References
References
- Remm, Maido; Christian E.V. Storm; Erik L.L. Sonnhammer (2001). "Automatic clustering of orthologs and in-paralogs from pairwise species comparisons". Journal of Molecular Biology. 314 (5): 1041–1052. CiteSeerX 10.1.1.328.6724. doi:10.1006/jmbi.2000.5197. PMID 11743721.
- O'Brien, K.P.; Remm, M.; Sonnhammer, E.L.L. (2005). "Inparanoid: a comprehensive database of eukaryotic orthologs". Nucleic Acids Research. 33 (Database Issue): D476–80. doi:10.1093/nar/gki107. PMC 540061. PMID 15608241.