Article · Wikipedia archive · Last revised Jul 9, 2026

Impentamine

Impentamine is a histamine antagonist selective for the H3 subtype.

Last revised
Jul 9, 2026
Read time
≈ 1 min
Length
152 w
Citations
2
Source
Wikipedia ↗
Impentamine
source ↗
Names
IUPAC name
5-(1H-imidazol-5-yl)pentan-1-amine
Identifiers
3D model (JSmol)
ChEMBL
ChemSpider
MeSH Impentamine
UNII
  • InChI=1S/C8H15N3/c9-5-3-1-2-4-8-6-10-7-11-8/h6-7H,1-5,9H2,(H,10,11) X markN
    Key: MZCJWLAXZRFUPI-UHFFFAOYSA-N X markN
  • InChI=1/C8H15N3/c9-5-3-1-2-4-8-6-10-7-11-8/h6-7H,1-5,9H2,(H,10,11)
    Key: MZCJWLAXZRFUPI-UHFFFAOYAF
  • C1=C(NC=N1)CCCCCN
Properties
C8H15N3
Molar mass 153.2248 g/mol
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
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Impentamine is a histamine antagonist selective for the H3 subtype.12

References

References

  1. Vollinga, RC; Menge, WM; Leurs, R; Timmerman, H (1995). "Homologs of histamine as histamine H3 receptor antagonists: a new potent and selective H3 antagonist, 4(5)-(5-aminopentyl)-1H-imidazole". Journal of Medicinal Chemistry. 38 (2): 266–71. doi:10.1021/jm00002a008. PMID 7830269.
  2. Van Der Goot, H; Timmerman, H (2000). "Selective ligands as tools to study histamine receptors". European Journal of Medicinal Chemistry. 35 (1): 5–20. doi:10.1016/S0223-5234(00)00101-X. PMID 10733599.