GPBP1

GPBP1
Identifiers
Aliases	GPBP1, GPBP, SSH6, VASCULIN, GC-rich promoter binding protein 1
External IDs	OMIM: 608412; MGI: 1920524; HomoloGene: 11292; GeneCards: GPBP1; OMA:GPBP1 - orthologs
Gene location (Human)
Chr.	Chromosome 5 (human)
End	57,264,679 bp
Gene location (Mouse)
Chr.	Chromosome 13 (mouse)
End	111,626,645 bp
RNA expression pattern
	Top expressed in
	ventricular zone; ; cardiac muscle tissue of right atrium; ; Achilles tendon; ; corpus callosum; ; gonad; ; myocardium of left ventricle; ; mucosa of paranasal sinus; ; epithelium of nasopharynx; ; ganglionic eminence; ; mucosa of ileum;
	Top expressed in
	zygote; ; primary oocyte; ; secondary oocyte; ; blood; ; cumulus cell; ; tail of embryo; ; spermatid; ; medial ganglionic eminence; ; hand; ; vestibular sensory epithelium;
	More reference expression data
	More reference expression data
Gene ontology
Molecular function	DNA-binding transcription factor activity; DNA binding; protein binding;
Cellular component	cytoplasm; intracellular membrane-bounded organelle; nucleus; cytosol; plasma membrane;
Biological process	positive regulation of transcription, DNA-templated; regulation of transcription, DNA-templated; transcription, DNA-templated;
	Sources:Amigo / QuickGO
Orthologs
	65056
	73274
	ENSG00000062194
	ENSMUSG00000032745
	Q86WP2
	Q6NXH3
	NM_001127235; NM_001127236; NM_001203246; NM_022913; NM_001331037
NM_001122963; NM_028487; NM_001361923; NM_001361924; NM_001361925;
	NM_001361926
	NP_001120707; NP_001120708; NP_001190175; NP_001317966; NP_075064
NP_001116435; NP_082763; NP_001348852; NP_001348853; NP_001348854;
	NP_001348855
	Wikidata
View/Edit Human	View/Edit Mouse

Vasculin is a protein that in humans is encoded by the GPBP1 gene.⁵⁶

References

GRCh38: Ensembl release 89: ENSG00000062194 – Ensembl, May 2017
GRCm38: Ensembl release 89: ENSMUSG00000032745 – Ensembl, May 2017
"Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
"Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
Bijnens AP, Gils A, Jutten B, Faber BC, Heeneman S, Kitslaar PJ, Tordoir JH, de Vries CJ, Kroon AA, Daemen MJ, Cleutjens KB (Oct 2003). "Vasculin, a novel vascular protein differentially expressed in human atherogenesis". Blood. 102 (8): 2803–10. doi:10.1182/blood-2003-01-0306. PMID 12842993.
"Entrez Gene: GPBP1 GC-rich promoter binding protein 1".

Further reading

Szafranski K, Schindler S, Taudien S, et al. (2008). "Violating the splicing rules: TG dinucleotides function as alternative 3' splice sites in U2-dependent introns". Genome Biol. 8 (8): R154. doi:10.1186/gb-2007-8-8-r154. PMC 2374985. PMID 17672918.
Mehrle A, Rosenfelder H, Schupp I, et al. (2006). "The LIFEdb database in 2006". Nucleic Acids Res. 34 (Database issue): D415–8. doi:10.1093/nar/gkj139. PMC 1347501. PMID 16381901.
Wiemann S, Arlt D, Huber W, et al. (2004). "From ORFeome to biology: a functional genomics pipeline". Genome Res. 14 (10B): 2136–44. doi:10.1101/gr.2576704. PMC 528930. PMID 15489336.
Hsu LC, Liu S, Abedinpour F, et al. (2003). "The murine G+C-rich promoter binding protein mGPBP is required for promoter-specific transcription". Mol. Cell. Biol. 23 (23): 8773–85. doi:10.1128/MCB.23.23.8773-8785.2003. PMC 262660. PMID 14612417.
Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. Bibcode:2002PNAS...9916899M. doi:10.1073/pnas.242603899. PMC 139241. PMID 12477932.
Simpson JC, Wellenreuther R, Poustka A, et al. (2001). "Systematic subcellular localization of novel proteins identified by large-scale cDNA sequencing". EMBO Rep. 1 (3): 287–92. doi:10.1093/embo-reports/kvd058. PMC 1083732. PMID 11256614.
Wiemann S, Weil B, Wellenreuther R, et al. (2001). "Toward a catalog of human genes and proteins: sequencing and analysis of 500 novel complete protein coding human cDNAs". Genome Res. 11 (3): 422–35. doi:10.1101/gr.GR1547R. PMC 311072. PMID 11230166.
Hartley JL, Temple GF, Brasch MA (2001). "DNA cloning using in vitro site-specific recombination". Genome Res. 10 (11): 1788–95. doi:10.1101/gr.143000. PMC 310948. PMID 11076863.

[refGRCh38Ensembl-1] GRCh38: Ensembl release 89: ENSG00000062194 – Ensembl, May 2017

[refGRCm38Ensembl-2] GRCm38: Ensembl release 89: ENSMUSG00000032745 – Ensembl, May 2017

[3] "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[4] "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[pmid12842993-5] Bijnens AP, Gils A, Jutten B, Faber BC, Heeneman S, Kitslaar PJ, Tordoir JH, de Vries CJ, Kroon AA, Daemen MJ, Cleutjens KB (Oct 2003). "Vasculin, a novel vascular protein differentially expressed in human atherogenesis". Blood. 102 (8): 2803–10. doi:10.1182/blood-2003-01-0306. PMID 12842993.

[entrez-6] "Entrez Gene: GPBP1 GC-rich promoter binding protein 1".

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