Article · Wikipedia archive · Last revised Jun 3, 2026

Germacrone

Germacrone is a sesquiterpene which has been isolated via distillation from the plant species Geranium macrorrhizum. It has shown antiviral properties in an animal model of influenza infection.

Last revised
Jun 3, 2026
Read time
≈ 1 min
Length
168 w
Citations
2
Source
Wikipedia ↗
Germacrone
source ↗
Names
Preferred IUPAC name
(3E,7E)-3,7-Dimethyl-10-(propan-2-ylidene)cyclodeca-3,7-dien-1-one
Identifiers
3D model (JSmol)
ChEBI
ChemSpider
EC Number
  • 834-535-3
KEGG
UNII
  • InChI=1S/C15H22O/c1-11(2)14-9-8-12(3)6-5-7-13(4)10-15(14)16/h7-8H,5-6,9-10H2,1-4H3/b12-8+,13-7+
    Key: CAULGCQHVOVVRN-SWZPTJTJSA-N
  • C/C/1=C\CC(=C(C)C)C(=O)C/C(=C/CC1)/C
Properties
C15H22O
Molar mass 218.340 g·mol−1
Hazards
Occupational safety and health (OHS/OSH):
Main hazards
 flammable
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).

Germacrone is a sesquiterpene which has been isolated via distillation from the plant species Geranium macrorrhizum.1 It has shown antiviral properties in an animal model of influenza infection.2

References

References

  1. Radulović, Niko S.; Dekić, Milan S.; Stojanović-Radić, Zorica Z.; Zoranić, Suad K. (2010). "Geranium macrorrhizum L. (Geraniaceae) essential oil: a potent agent against Bacillus subtilis". Chemistry & Biodiversity. 7 (11): 2783–800. doi:10.1002/cbdv.201000100. PMID 21072778. S2CID 7366166.
  2. Liao, Q; Qian, Z; Liu, R; An, L; Chen, X (2013). "Germacrone inhibits early stages of influenza virus infection". Antiviral Research. 100 (3): 578–88. doi:10.1016/j.antiviral.2013.09.021. PMID 24095670.