Article · Wikipedia archive · Last revised May 28, 2026

Fluopyram

Fluopyram is a synthetic fungicide and nematicide used in agriculture. It is used to control fungal diseases such as gray mold, powdery mildew, apple scab, Alternaria, Sclerotinia, and Monilinia. It is an inhibitor of succinate dehydrogenase.

Last revised
May 28, 2026
Read time
≈ 1 min
Length
302 w
Citations
8
Source
Wikipedia ↗
Fluopyram
source ↗
Names
Preferred IUPAC name
N-{2-[3-Chloro-5-(trifluoromethyl)pyridin-2-yl]ethyl}-2-(trifluoromethyl)benzamide
Identifiers
3D model (JSmol)
ChemSpider
ECHA InfoCard 100.127.749
UNII
  • InChI=1S/C16H11ClF6N2O/c17-12-7-9(15(18,19)20)8-25-13(12)5-6-24-14(26)10-3-1-2-4-11(10)16(21,22)23/h1-4,7-8H,5-6H2,(H,24,26)
    Key: KVDJTXBXMWJJEF-UHFFFAOYSA-N
  • FC(F)(F)c1ccccc1C(=O)NCCc2ncc(cc2Cl)C(F)(F)F
Properties
C16H11ClF6N2O
Molar mass 396.72 g·mol−1
Melting point 117.5 °C (243.5 °F; 390.6 K)1
Boiling point 318–321 °C (604–610 °F; 591–594 K)1
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).

Fluopyram is a synthetic fungicide and nematicide used in agriculture.23 It is used to control fungal diseases such as gray mold (Botrytis cinerea), powdery mildew, apple scab, Alternaria, Sclerotinia, and Monilinia. It is an inhibitor of succinate dehydrogenase (SDHI fungicide).4

Regulation

Developed and produced by Bayer, it was approved in 2012 by the U.S. Environmental Protection Agency4 and in 2013 it was approved in the EU for use as an active ingredient in pesticides.5

Pesticide products containing fluopyram have been banned in Denmark because the chemical can degrade into trifluoroacetic acid, which can then contaminate groundwater and not decompose.6

References

References

  1. "Fluopyram" (PDF). Food and Agriculture Organization of the United Nations.
  2. Grabau, Zane J.; Liu, Chang; Schumacher, Lesley A.; Small, Ian M.; Wright, David L. (February 2021). "In-furrow fluopyram nematicide efficacy for Rotylenchulus reniformis management in cotton production". Crop Protection. 140 105423. Bibcode:2021CrPro.14005423G. doi:10.1016/j.cropro.2020.105423. S2CID 226354918.
  3. Faske, TR; Hurd, K (December 2015). "Sensitivity of Meloidogyne incognita and Rotylenchulus reniformis to Fluopyram". Journal of Nematology. 47 (4): 316–21. PMC 4755706. PMID 26941460.
  4. "Fluopyram". New Active Ingredient Review. Minnesota Department of Agriculture. April 2012. Archived from the original on 2017-04-26. Retrieved 2015-09-16.
  5. "Durchführungsverordnung (EU) Nr. 802/2013 Der Kommission" (in German). August 2013.
  6. "Denmark bans more PFAS pesticides to protect groundwater". Pesticide Action Network Europe. October 6, 2025. Retrieved 6 November 2025.