| EIF4A2 |
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| Identifiers |
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| Aliases | EIF4A2, BM-010, DDX2B, EIF4A, EIF4F, eIF-4A-II, eIF4A-II, eukaryotic translation initiation factor 4A2 |
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| External IDs | OMIM: 601102; MGI: 106906; HomoloGene: 1487; GeneCards: EIF4A2; OMA:EIF4A2 - orthologs |
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| Gene location (Mouse) |
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 | | Chr. | Chromosome 16 (mouse)2 |
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| | Band | 16 B1|16 13.93 cM | Start | 22,926,194 bp2 |
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| End | 22,932,886 bp2 |
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| RNA expression pattern |
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| Bgee | | Human | Mouse (ortholog) |
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| Top expressed in | - secondary oocyte
- endothelial cell
- cerebellar vermis
- germinal epithelium
- postcentral gyrus
- superior frontal gyrus
- lateral nuclear group of thalamus
- Region I of hippocampus proper
- Brodmann area 23
- primary visual cortex
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| | Top expressed in | - dentate gyrus of hippocampal formation granule cell
- diencephalon
- hypothalamus
- hippocampus proper
- cerebellar cortex
- primary visual cortex
- superior frontal gyrus
- olfactory bulb
- uterus
- ovary
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| | More reference expression data |
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| BioGPS | |
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| Wikidata |
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Eukaryotic initiation factor 4A-II is a protein that in humans is encoded by the EIF4A2 gene.56
References
References
Further reading
Further reading
- Maruyama K, Sugano S (1994). "Oligo-capping: a simple method to replace the cap structure of eukaryotic mRNAs with oligoribonucleotides". Gene. 138 (1–2): 171–4. doi:10.1016/0378-1119(94)90802-8. PMID 8125298.
- Suzuki Y, Yoshitomo-Nakagawa K, Maruyama K, et al. (1997). "Construction and characterization of a full length-enriched and a 5'-end-enriched cDNA library". Gene. 200 (1–2): 149–56. doi:10.1016/S0378-1119(97)00411-3. PMID 9373149.
- Li W, Belsham GJ, Proud CG (2001). "Eukaryotic initiation factors 4A (eIF4A) and 4G (eIF4G) mutually interact in a 1:1 ratio in vivo". J. Biol. Chem. 276 (31): 29111–5. doi:10.1074/jbc.C100284200. PMID 11408474.
- Kyono K, Miyashiro M, Taguchi I (2002). "Human eukaryotic initiation factor 4AII associates with hepatitis C virus NS5B protein in vitro". Biochem. Biophys. Res. Commun. 292 (3): 659–66. doi:10.1006/bbrc.2002.6702. PMID 11922617.
- Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. Bibcode:2002PNAS...9916899M. doi:10.1073/pnas.242603899. PMC 139241. PMID 12477932.
- Gerhard DS, Wagner L, Feingold EA, et al. (2004). "The Status, Quality, and Expansion of the NIH Full-Length cDNA Project: The Mammalian Gene Collection (MGC)". Genome Res. 14 (10B): 2121–7. doi:10.1101/gr.2596504. PMC 528928. PMID 15489334.
- Sarkar M, Das S, Bandyopadhaya A, et al. (2005). "Upregulation of human mitochondrial NADH dehydrogenase subunit 5 in intestinal epithelial cells is modulated by Vibrio cholerae pathogenesis". FEBS Lett. 579 (16): 3449–60. doi:10.1016/j.febslet.2005.05.012. PMID 15946665. S2CID 25850943.
- Feng P, Everly DN, Read GS (2005). "mRNA Decay during Herpes Simplex Virus (HSV) Infections: Protein-Protein Interactions Involving the HSV Virion Host Shutoff Protein and Translation Factors eIF4H and eIF4A". J. Virol. 79 (15): 9651–64. doi:10.1128/JVI.79.15.9651-9664.2005. PMC 1181552. PMID 16014927.
- Cheyssac C, Dina C, Leprêtre F, et al. (2006). "EIF4A2 is a positional candidate gene at the 3q27 locus linked to type 2 diabetes in French families". Diabetes. 55 (4): 1171–6. doi:10.2337/diabetes.55.04.06.db05-1298. PMID 16567544.
- Ewing RM, Chu P, Elisma F, et al. (2007). "Large-scale mapping of human protein–protein interactions by mass spectrometry". Mol. Syst. Biol. 3 (1): 89. doi:10.1038/msb4100134. PMC 1847948. PMID 17353931.
External links
External links
- Overview of all the structural information available in the PDB for UniProt: Q14240 (Human Eukaryotic initiation factor 4A-II (EIF4A2)) at the PDBe-KB.
