DNTTIP2

DNTTIP2
Identifiers
Aliases	DNTTIP2, ERBP, FCF2, HSU15552, LPTS-RP2, TdIF2, deoxynucleotidyltransferase terminal interacting protein 2
External IDs	OMIM: 611199; MGI: 1923173; HomoloGene: 124162; GeneCards: DNTTIP2; OMA:DNTTIP2 - orthologs
Gene location (Human)
Chr.	Chromosome 1 (human)
End	93,879,918 bp
Gene location (Mouse)
Chr.	Chromosome 3 (mouse)
End	122,078,920 bp
RNA expression pattern
	Top expressed in
	Achilles tendon; ; gonad; ; gingival epithelium; ; islet of Langerhans; ; testicle; ; ventricular zone; ; glutes; ; biceps brachii; ; Skeletal muscle tissue of biceps brachii; ; olfactory zone of nasal mucosa;
	Top expressed in
	otic placode; ; otic vesicle; ; saccule; ; secondary oocyte; ; tail of embryo; ; genital tubercle; ; epiblast; ; morula; ; morula; ; zygote;
	More reference expression data
	More reference expression data
Gene ontology
Molecular function	RNA binding;
Cellular component	nucleus; nucleolus;
Biological process	regulation of transcription, DNA-templated; transcription, DNA-templated;
	Sources:Amigo / QuickGO
Orthologs
	30836
	99480
	ENSG00000067334
	ENSMUSG00000039756
	Q5QJE6
	Q8R2M2
	NM_014597
	NM_153806
	NP_055412
	NP_722501
	Wikidata
View/Edit Human	View/Edit Mouse

Deoxynucleotidyltransferase terminal-interacting protein 2 is an enzyme that in humans is encoded by the DNTTIP2 gene.⁵⁶

Interactions

DNTTIP2 has been shown to interact with Estrogen receptor alpha.⁵

References

GRCh38: Ensembl release 89: ENSG00000067334 – Ensembl, May 2017
GRCm38: Ensembl release 89: ENSMUSG00000039756 – Ensembl, May 2017
"Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
"Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
Bu H, Kashireddy P, Chang J, Zhu YT, Zhang Z, Zheng W, Rao SM, Zhu YJ (Mar 2004). "ERBP, a novel estrogen receptor binding protein enhancing the activity of estrogen receptor". Biochem Biophys Res Commun. 317 (1): 54–9. doi:10.1016/j.bbrc.2004.02.179. PMID 15047147.
"Entrez Gene: DNTTIP2 deoxynucleotidyltransferase, terminal, interacting protein 2".

Further reading

Soares-da-Silva P, Fernandes MH (1992). "Sodium-dependence and ouabain-sensitivity of the synthesis of dopamine in renal tissues of the rat". Br. J. Pharmacol. 105 (4): 811–6. doi:10.1111/j.1476-5381.1992.tb09062.x. PMC 1908707. PMID 1504714.
Lim HD (1992). "Making an alternative occlusal splint". The Journal of Prosthetic Dentistry. 67 (4): 572–3. doi:10.1016/0022-3913(92)90094-Q. PMID 1507147.
Maruyama K, Sugano S (1994). "Oligo-capping: a simple method to replace the cap structure of eukaryotic mRNAs with oligoribonucleotides". Gene. 138 (1–2): 171–4. doi:10.1016/0378-1119(94)90802-8. PMID 8125298.
Suzuki Y, Yoshitomo-Nakagawa K, Maruyama K, et al. (1997). "Construction and characterization of a full length-enriched and a 5'-end-enriched cDNA library". Gene. 200 (1–2): 149–56. doi:10.1016/S0378-1119(97)00411-3. PMID 9373149.
Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. Bibcode:2002PNAS...9916899M. doi:10.1073/pnas.242603899. PMC 139241. PMID 12477932.
Fujita K, Shimazaki N, Ohta Y, et al. (2004). "Terminal deoxynucleotidyltransferase forms a ternary complex with a novel chromatin remodeling protein with 82 kDa and core histone". Genes Cells. 8 (6): 559–71. doi:10.1046/j.1365-2443.2003.00656.x. PMID 12786946. S2CID 25223336.
Ota T, Suzuki Y, Nishikawa T, et al. (2004). "Complete sequencing and characterization of 21,243 full-length human cDNAs". Nat. Genet. 36 (1): 40–5. doi:10.1038/ng1285. PMID 14702039.
Rempola B, Karkusiewicz I, Piekarska I, Rytka J (2006). "Fcf1p and Fcf2p are novel nucleolar Saccharomyces cerevisiae proteins involved in pre-rRNA processing". Biochem. Biophys. Res. Commun. 346 (2): 546–54. doi:10.1016/j.bbrc.2006.05.140. PMID 16762320.

[refGRCh38Ensembl-1] GRCh38: Ensembl release 89: ENSG00000067334 – Ensembl, May 2017

[refGRCm38Ensembl-2] GRCm38: Ensembl release 89: ENSMUSG00000039756 – Ensembl, May 2017

[3] "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[4] "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[pmid15047147-5] Bu H, Kashireddy P, Chang J, Zhu YT, Zhang Z, Zheng W, Rao SM, Zhu YJ (Mar 2004). "ERBP, a novel estrogen receptor binding protein enhancing the activity of estrogen receptor". Biochem Biophys Res Commun. 317 (1): 54–9. doi:10.1016/j.bbrc.2004.02.179. PMID 15047147.

[entrez-6] "Entrez Gene: DNTTIP2 deoxynucleotidyltransferase, terminal, interacting protein 2".

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