Depression may refer to:
Mental health
- Depression (mood), a state of low mood and aversion to activity
- Mood disorders characterized by depression are commonly referred to as simply depression, including:
- Major depressive disorder, also known as clinical depression
- Bipolar disorder, also known as manic depression
- Dysthymia, also known as persistent depressive disorder
- Psychotic depression, depressive episode that is accompanied by psychotic symptoms
- Seasonal affective disorder, also known as seasonal depression
- Atypical depression, characterized by improved mood in response to positive events
- Long-term depression, reduction of neuronal synapse efficacy
Economics
- Economic depression, a sustained, long-term downturn in economic activity in one or more economies
- Great Depression, a severe economic depression during the 1930s, commonly referred to as simply the Depression
- Long Depression, an economic depression during 1873–96, known at the time as the Great Depression
Biology
- Depression (kinesiology), an anatomical term of motion, refers to downward movement, the opposite of elevation
- Depression (physiology), a reduction in a biological variable or the function of an organ
- Central nervous system depression, physiological depression of the central nervous system that can result in loss of consciousness
Earth science
- Depression (geology), a landform sunken or depressed below the surrounding area
- Depression (weather), an area of low atmospheric pressure characterized by rain and unstable weather
Art
- "Depressed" (song), a song by English singer-songwriter Anne-Marie, 2025