XTP3-transactivated gene A protein

DCTPP1
Available structures
PDB	Ortholog search: PDBe RCSB
List of PDB id codes
	2A3Q, 2OIE, 2OIG, 2Q4P
Identifiers
Aliases	DCTPP1, RS21C6, XTP3TPA, CDA03, XTP3-transactivated gene A protein, dCTP pyrophosphatase 1
External IDs	OMIM: 615840; MGI: 1913672; HomoloGene: 11329; GeneCards: DCTPP1; OMA:DCTPP1 - orthologs
Gene location (Human)
Chr.	Chromosome 16 (human)
End	30,430,030 bp
Gene location (Mouse)
Chr.	Chromosome 7 (mouse)
End	126,859,881 bp
RNA expression pattern
	Top expressed in
	mucosa of transverse colon; ; rectum; ; parotid gland; ; oocyte; ; gonad; ; mucosa of sigmoid colon; ; endothelial cell; ; nasal epithelium; ; hair follicle; ; pancreatic ductal cell;
	Top expressed in
	embryo; ; embryo; ; epiblast; ; yolk sac; ; otic placode; ; primitive streak; ; somite; ; ventricular zone; ; medial ganglionic eminence; ; morula;
	More reference expression data
	More reference expression data
Gene ontology
Molecular function	nucleotide binding; pyrophosphatase activity; protein binding; hydrolase activity; magnesium ion binding; metal ion binding; identical protein binding; pyrimidine deoxyribonucleotide binding; dCTP diphosphatase activity; nucleoside-triphosphate diphosphatase activity;
Cellular component	cytoplasm; cytosol; nucleus; mitochondrion;
Biological process	protein homotetramerization; dCTP catabolic process; nucleoside triphosphate catabolic process; DNA protection; dTTP catabolic process;
	Sources:Amigo / QuickGO
Orthologs
	79077
	66422
	ENSG00000179958
	ENSMUSG00000042462
	Q9H773
	Q9QY93
	NM_024096
	NM_023203
	NP_077001
	NP_075692
	Wikidata
View/Edit Human	View/Edit Mouse

dCTP pyrophosphatase 1 is an enzyme that in humans is encoded by the DCTPP1 gene.⁵⁶

References

GRCh38: Ensembl release 89: ENSG00000179958 – Ensembl, May 2017
GRCm38: Ensembl release 89: ENSMUSG00000042462 – Ensembl, May 2017
"Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
"Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
Moroz OV, Murzin AG, Makarova KS, Koonin EV, Wilson KS, Galperin MY (Mar 2005). "Dimeric dUTPases, HisE, and MazG belong to a new superfamily of all-alpha NTP pyrophosphohydrolases with potential "house-cleaning" functions". J Mol Biol. 347 (2): 243–55. doi:10.1016/j.jmb.2005.01.030. PMID 15740738.
"Entrez Gene: XTP3TPA XTP3-transactivated protein A".

Further reading

Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. Bibcode:2002PNAS...9916899M. doi:10.1073/pnas.242603899. PMC 139241. PMID 12477932.
Stelzl U, Worm U, Lalowski M, et al. (2005). "A human protein-protein interaction network: a resource for annotating the proteome". Cell. 122 (6): 957–68. doi:10.1016/j.cell.2005.08.029. hdl:11858/00-001M-0000-0010-8592-0. PMID 16169070.
Rual JF, Venkatesan K, Hao T, et al. (2005). "Towards a proteome-scale map of the human protein-protein interaction network". Nature. 437 (7062): 1173–8. Bibcode:2005Natur.437.1173R. doi:10.1038/nature04209. PMID 16189514. S2CID 4427026.

[refGRCh38Ensembl-1] GRCh38: Ensembl release 89: ENSG00000179958 – Ensembl, May 2017

[refGRCm38Ensembl-2] GRCm38: Ensembl release 89: ENSMUSG00000042462 – Ensembl, May 2017

[3] "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[4] "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[pmid15740738-5] Moroz OV, Murzin AG, Makarova KS, Koonin EV, Wilson KS, Galperin MY (Mar 2005). "Dimeric dUTPases, HisE, and MazG belong to a new superfamily of all-alpha NTP pyrophosphohydrolases with potential "house-cleaning" functions". J Mol Biol. 347 (2): 243–55. doi:10.1016/j.jmb.2005.01.030. PMID 15740738.

[entrez-6] "Entrez Gene: XTP3TPA XTP3-transactivated protein A".

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See also

References

Further reading