Article · Wikipedia archive · Last revised Jun 13, 2026

Daniel S. Pine

Daniel S. Pine is an American psychiatrist and researcher specializing in pediatric mental health, novel therapeutics, mood and anxiety disorders, and developmental neuroscience. He is Chief of the Emotion and Development Branch and of the Section on Development and Affective Neuroscience at the National Institute of Mental Health (NIMH).

Last revised
Jun 13, 2026
Read time
≈ 4 min
Length
1,025 w
Citations
32
Source
Wikipedia ↗
Daniel S. Pine
Born (1963-04-19) April 19, 1963
Hyannis, Massachusetts, U.S.
EducationGrinnell College (BA); University of Chicago Pritzker School of Medicine (MD)
Known forResearch on pediatric mood and anxiety disorders and brain function
Scientific career
FieldsPsychiatry; child and adolescent psychiatry; developmental neuroscience
InstitutionsNational Institute of Mental Health (NIMH)

Daniel S. Pine (born April 19, 1963, in Hyannis, Massachusetts) is an American psychiatrist and researcher specializing in pediatric mental health, novel therapeutics, mood and anxiety disorders, and developmental neuroscience. He is Chief of the Emotion and Development Branch and of the Section on Development and Affective Neuroscience at the National Institute of Mental Health (NIMH).

Education

After attending high school in Decatur, Illinois, Pine earned a B.A. in anthropology from Grinnell College in 1985 and an M.D. from the University of Chicago Pritzker School of Medicine in 1990. He completed postgraduate training in psychiatry, child psychiatry, and child psychiatry research at Columbia University, Columbia Presbyterian Medical Center, and the New York State Psychiatric Institute.123

Career

Between 1993 and 2000, Pine worked in clinical and academic positions at Columbia University and the New York State Psychiatric Institute.34

Pine joined the National Institute of Mental Health (NIMH) Intramural Research Program in 2000.5678 From 2000 to 2010, he was Chief of Child and Adolescent Research in the Mood and Anxiety Disorders Program. Since 2000, he has been Chief of the Section on Development and Affective Neuroscience at the institute.9101112 He served as Chief of the Emotion and Development Branch from 2006 to 2009, and he became Chief again in 2019.

Pine's research has focused on relations among psychopathology, brain development, and stress, anxiety, and mood symptoms.1314151617 His research group has examined how pediatric mood and anxiety disorders relate to activity in brain regions including the amygdala and prefrontal cortex, and has also researched the treatment of pediatric emotional disorders.181920 Pine has authored over 700 peer-reviewed articles.1 He has served as an editor or on editorial boards of academic journals including the American Journal of Psychiatry, Biological Psychiatry, Journal of Affective Disorders, Psychological Medicine, Development and Psychopathology, and Clinical Psychological Science.2122

Pine received the Blanche F. Ittelson Award from the American Psychiatric Association in 2000, the Joel Elkes Award from the American College of Neuropsychopharmacology in 2008.232425 He was selected as a Distinguished Investigator at the National Institute of Health in 2019.26 He is a member of the National Academy of Medicine.27282930

References

References

  1. "Daniel Pine, M.D. | Principal Investigators | NIH Intramural Research Program". irp.nih.gov. Retrieved 2026-01-23.
  2. "Using Neuroscience to Inform Clinical Thinking: Applications to Pediatric Anxiety". University of Pittsburgh Department of Psychiatry. 2019-01-11. Retrieved 2026-01-23.
  3. "Daniel Pine, MD". Child Mind Institute. Retrieved 2026-01-23.
  4. "Dr. Daniel S. Pine MD". US News. Retrieved 3 May 2026.
  5. "Reward-Processing Issues in Depression | Psychology Today". www.psychologytoday.com. Retrieved 2026-01-23.
  6. "Section on Development and Affective Neuroscience: Meet the Team - National Institute of Mental Health (NIMH)". www.nimh.nih.gov. Retrieved 2026-01-23.
  7. "Daniel Pine - National Institute of Mental Health (NIMH)". www.nimh.nih.gov. Retrieved 2026-01-23.
  8. "What's new in anxiety research?". NIH MedlinePlus Magazine. Retrieved 2026-01-23.
  9. "Anxiety Disorders in DSM-5 and Beyond | 2013-09-01 | CARLAT PUBLISHING". www.thecarlatreport.com. Retrieved 2026-01-23.
  10. Moran, Mark (2016-10-06). "Neuroscientists Propose New Model for Understanding Fear, Anxiety". Psychiatric News. 51 (19): 1. doi:10.1176/appi.pn.2016.9b13.
  11. "Child and Adolescent Psychiatry Residency Training Program - Additional Opportunities - For Professionals". NewYork-Presbyterian. Retrieved 2026-01-23.
  12. "Developing Neuroscience Tools to Improve Treatments | Brain & Behavior Research Foundation". Bbrfoundation. 2017-07-19. Retrieved 2026-01-23.
  13. Abend, Rany; Karni, Avi; Sadeh, Avi; Fox, Nathan A.; Pine, Daniel S.; Bar-Haim, Yair (2013-04-30). "Learning to Attend to Threat Accelerates and Enhances Memory Consolidation". PLOS ONE. 8 (4) e62501. Bibcode:2013PLoSO...862501A. doi:10.1371/journal.pone.0062501. ISSN 1932-6203. PMC 3640061. PMID 23638100.
  14. LeDoux, Joseph E.; Pine, Daniel S. (November 2016). "Using Neuroscience to Help Understand Fear and Anxiety: A Two-System Framework". American Journal of Psychiatry. 173 (11): 1083–1093. doi:10.1176/appi.ajp.2016.16030353. PMID 27609244.
  15. Lau, Jennifer Y.; Britton, Jennifer C.; Nelson, Eric E.; Angold, Adrian; Ernst, Monique; Goldwin, Michelle; Grillon, Christian; Leibenluft, Ellen; Lissek, Shmuel; Norcross, Maxine; Shiffrin, Nina; Pine, Daniel S. (2011-03-15). "Distinct neural signatures of threat learning in adolescents and adults". Proceedings of the National Academy of Sciences. 108 (11): 4500–4505. Bibcode:2011PNAS..108.4500L. doi:10.1073/pnas.1005494108. PMC 3060221. PMID 21368210.
  16. Pine, Daniel S.; Cohen, Patricia; Gurley, Diana; Brook, Judith; Ma, Yuju (1998-01-01). "The Risk for Early-Adulthood Anxiety and Depressive Disorders in Adolescents With Anxiety and Depressive Disorders". Archives of General Psychiatry. 55 (1): 56–64. doi:10.1001/archpsyc.55.1.56. ISSN 0003-990X. PMID 9435761.
  17. Pine, Daniel S. (May 2019). "Heterogeneity in Major Depressive Disorder: Lessons From Developmental Research on Irritability". American Journal of Psychiatry. 176 (5): 331–332. doi:10.1176/appi.ajp.2019.19020214. PMID 31039634.
  18. Eldar, Sharon; Apter, Alan; Lotan, Daniel; Edgar, Koraly Perez; Naim, Reut; Fox, Nathan A.; Pine, Daniel S.; Bar-Haim, Yair (February 2012). "Attention bias modification treatment for pediatric anxiety disorders: a randomized controlled trial". The American Journal of Psychiatry. 169 (2): 213–220. doi:10.1176/appi.ajp.2011.11060886. ISSN 1535-7228. PMC 3491316. PMID 22423353.
  19. McClure, Erin B.; Adler, Abby; Monk, Christopher S.; Cameron, Jennifer; Smith, Samantha; Nelson, Eric E.; Leibenluft, Ellen; Ernst, Monique; Pine, Daniel S. (March 2007). "fMRI predictors of treatment outcome in pediatric anxiety disorders". Psychopharmacology. 191 (1): 97–105. doi:10.1007/s00213-006-0542-9. ISSN 0033-3158. PMID 16972100.
  20. Guyer, Amanda E.; Lau, Jennifer Y. F.; McClure-Tone, Erin B.; Parrish, Jessica; Shiffrin, Nina D.; Reynolds, Richard C.; Chen, Gang; Blair, R. J. R.; Leibenluft, Ellen; Fox, Nathan A.; Ernst, Monique; Pine, Daniel S.; Nelson, Eric E. (November 2008). "Amygdala and ventrolateral prefrontal cortex function during anticipated peer evaluation in pediatric social anxiety". Archives of General Psychiatry. 65 (11): 1303–1312. doi:10.1001/archpsyc.65.11.1303. ISSN 1538-3636. PMC 2717208. PMID 18981342.
  21. "Editorial board - Journal of Affective Disorders | ScienceDirect.com by Elsevier". www.sciencedirect.com. Retrieved 2026-01-23.
  22. "Clinical Psychological Science Editorial Board". Association for Psychological Science - APS. Retrieved 2026-01-23.
  23. dotCMS. "Daniel Pine - The Ross Center". www.rosscenter.com. Retrieved 2026-01-23.
  24. "News & Notes". Psychiatric Services. 51 (6): 830–832. 2000. doi:10.1176/appi.ps.51.6.830.
  25. "Joel Elkes Research Previous Award Winners". ACNP. Retrieved 2026-01-23.
  26. "Principal Investigators - National Institute of Mental Health (NIMH)". www.nimh.nih.gov. Retrieved 2026-01-23.
  27. "NAM Member Listing" (PDF). National academy of Medicine. Retrieved 3 May 2026.
  28. "2026 Daniel S. Pine: Psychology Researcher – H-Index, Publications & Awards". Research.com. Retrieved 2026-01-23.
  29. "The National Academy of Medicine | NIH Intramural Research Program". irp.nih.gov. Retrieved 2026-01-23.
  30. "Three NIH Scientists Elected into IOM - National Institute of Mental Health (NIMH)". www.nimh.nih.gov. 2013-10-21. Retrieved 2026-01-23.