Bioanalytical equivalent

A bioanalytical equivalent (BEQ) is a unit of measure in the field of environmental toxicology. It is widely used for mixtures and environmental samples to reflect the potential threat of pollutants in the environment and can be obtained by bioassays or using chemical analysis combined with relative potencies.¹ One example is the bioassay CALUX for testing dioxins and dioxin-like compounds.²

References

Zhou, Shangbo; Peng, Shuchan; Brack, Werner; Doering, Jon A.; Seiler, Thomas-Benjamin; Hollert, Henner (April 2021). "Bioanalytical equivalents and relative potencies for predicting the biological effects of mixtures". Science of the Total Environment. 763 143030. doi:10.1016/j.scitotenv.2020.143030. PMID 33129534.
Baston, David S.; Denison, Michael S. (February 2011). "Considerations for potency equivalent calculations in the Ah receptor-based CALUX bioassay: Normalization of superinduction results for improved sample potency estimation". Talanta. 83 (5): 1415–1421. doi:10.1016/j.talanta.2010.11.035. PMC 3036574. PMID 21238730.

[1] Zhou, Shangbo; Peng, Shuchan; Brack, Werner; Doering, Jon A.; Seiler, Thomas-Benjamin; Hollert, Henner (April 2021). "Bioanalytical equivalents and relative potencies for predicting the biological effects of mixtures". Science of the Total Environment. 763 143030. doi:10.1016/j.scitotenv.2020.143030. PMID 33129534.

[2] Baston, David S.; Denison, Michael S. (February 2011). "Considerations for potency equivalent calculations in the Ah receptor-based CALUX bioassay: Normalization of superinduction results for improved sample potency estimation". Talanta. 83 (5): 1415–1421. doi:10.1016/j.talanta.2010.11.035. PMC 3036574. PMID 21238730.

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