Article · Wikipedia archive · Last revised Jun 23, 2026

Altizide

Altizide is a thiazide diuretic. In combination with spironolactone it is sold under the brand name of Aldactacine and Aldactazine by Pfizer and other names by other companies.

Last revised
Jun 23, 2026
Read time
≈ 1 min
Length
156 w
Citations
2
Source
Wikipedia ↗
Altizide
source ↗
Names
IUPAC name
(3R)-3-[(Allylsulfanyl)methyl]-6-chloro-3,4-dihydro-2H-1,2,4-benzothiadiazine-7-sulfonamide 1,1-dioxide
Other names
  • Althiazide
  • CB 8093
  • P 1779
  • Altizidum
Identifiers
3D model (JSmol)
ChEMBL
ChemSpider
ECHA InfoCard 100.024.541
KEGG
UNII
  • InChI=1S/C11H14ClN3O4S3/c1-2-3-20-6-11-14-8-4-7(12)9(21(13,16)17)5-10(8)22(18,19)15-11/h2,4-5,11,14-15H,1,3,6H2,(H2,13,16,17)/t11-/m1/s1 checkY
    Key: VGLGVJVUHYTIIU-LLVKDONJSA-N checkY
  • InChI=1/C11H14ClN3O4S3/c1-2-3-20-6-11-14-8-4-7(12)9(21(13,16)17)5-10(8)22(18,19)15-11/h2,4-5,11,14-15H,1,3,6H2,(H2,13,16,17)/t11-/m1/s1
    Key: VGLGVJVUHYTIIU-LLVKDONJBT
  • O=S(=O)(c1c(Cl)cc2c(c1)S(=O)(=O)N[C@@H](N2)CSC\C=C)N
  • C=CCSCC1NC2=CC(=C(C=C2S(=O)(=O)N1)S(=O)(=O)N)Cl
Properties
C11H14ClN3O4S3
Molar mass 383.89456
Density 1.502 g/mL
Boiling point 625.8 °C (1,158.4 °F; 898.9 K)
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
☒N verify (what is checkY☒N ?)

Altizide is a thiazide diuretic. In combination with spironolactone it is sold under the brand name of Aldactacine and Aldactazine by Pfizer and other names by other companies.12

References

References

  1. "Altizide". drugs.com.
  2. Dueymes, J. M (1990). "Clinical update: spironolactone and altizide as monotherapy in systemic hypertension". The American Journal of Cardiology. 65 (23): 20K–23K. doi:10.1016/0002-9149(90)91272-8. PMID 2191585.