Article · Wikipedia archive · Last revised Jun 8, 2026

Alpha,Beta-D

Alpha,Beta-D, or α,β-D, also known as α,β-dideuteromescaline, is a psychedelic drug of the phenethylamine and scaline families related to mescaline. It is the deuterated isotopologue of mescaline in which one hydrogen atom at the α position and one hydrogen atom at the β position have been replaced with the deuterium isotopes.

Last revised
Jun 8, 2026
Read time
≈ 1 min
Length
253 w
Citations
11
Source
Alpha,Beta-D
Clinical data
Other namesα,β-D; α,β-Dideuteromescaline; α,β-Dideutero-3,4,5-trimethoxyphenethylamine
Routes of
administration
Oral1
Drug classSerotonergic psychedelic; Hallucinogen
ATC code
  • None
Pharmacokinetic data
Onset of actionSomewhat more rapid than mescaline1
Duration of actionUnknown1
Identifiers
  • 2-(3,4,5-trimethoxyphenyl)(1,2-2H2)ethan-1-amine
Chemical and physical data
FormulaC11H15D2NO3
Molar mass213.272 g·mol−1
3D model (JSmol)
  • COC1=CC(C(C(N)[2H])[2H])=CC(OC)=C1OC
  • InChI=1S/C11H17NO3/c1-13-9-6-8(4-5-12)7-10(14-2)11(9)15-3/h6-7H,4-5,12H2,1-3H3/i4D,5D
  • Key:RHCSKNNOAZULRK-KFRNQKGQSA-N

Alpha,Beta-D, or α,β-D, also known as α,β-dideuteromescaline, is a psychedelic drug of the phenethylamine and scaline families related to mescaline.1 It is the deuterated isotopologue of mescaline in which one hydrogen atom at the α position and one hydrogen atom at the β position have been replaced with the deuterium isotopes.1

According to Daniel Trachsel in his book Phenethylamine: von der Struktur zur Funktion (Phenethylamines: From Structure to Function), α,β-D at a dose of 250 mg orally produces effects comparable to an equivalent dose of mescaline, but had a somewhat more rapid onset.1 This information was based on anonymous personal communication to Trachsel in 2009.1 The similar potency of α,β-D to mescaline is in contrast to the case of α-D (α,α-dideuteromescaline), which was reported to be roughly one-third more potent than mescaline based on limited testing.1

The chemical synthesis of α,β-D has been described.1 It has four possible theoretical stereoisomers.1

α,β-D was first described in the scientific literature by Trachsel in his book in 2013.1

See also

See also

References

References

  1. Trachsel D, Lehmann D, Enzensperger C (2013). Phenethylamine: von der Struktur zur Funktion [Phenethylamines: From Structure to Function]. Nachtschatten-Science (in German) (1 ed.). Solothurn: Nachtschatten-Verlag. ISBN 978-3-03788-700-4. OCLC 858805226. Archived from the original on 21 August 2025.
External links