Article · Wikipedia archive · Last revised Jul 6, 2026

5-HT2 receptor

The 5-HT2 receptors are a subfamily of 5-HT receptors that bind the endogenous neurotransmitter serotonin (5-hydroxytryptamine, 5-HT). The 5-HT2 subfamily consists of three G protein-coupled receptors (GPCRs) which are coupled to Gq/G11 and mediate excitatory neurotransmission, including 5-HT2A, 5-HT2B, and 5-HT2C. For more information, please see the respective main articles of the individual subtypes:5-HT2A receptor 5-HT2B receptor 5-HT2C receptor

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Jul 6, 2026

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The 5-HT₂ receptors are a subfamily of 5-HT receptors that bind the endogenous neurotransmitter serotonin (5-hydroxytryptamine, 5-HT).¹ The 5-HT₂ subfamily consists of three G protein-coupled receptors (GPCRs) which are coupled to G_q/G₁₁ and mediate excitatory neurotransmission,² including 5-HT_2A, 5-HT_2B, and 5-HT_2C. For more information, please see the respective main articles of the individual subtypes:

See also

See also

References

References

Hoyer D, Clarke DE, Fozard JR, Hartig PR, Martin GR, Mylecharane EJ, Saxena PR, Humphrey PP (1994). "International Union of Pharmacology classification of receptors for 5-hydroxytryptamine (Serotonin)". Pharmacol. Rev. 46 (2): 157–203. PMID 7938165.
Eison AS, Mullins UL (1996). "Regulation of central 5-HT2A receptors: a review of in vivo studies". Behavioural Brain Research. 73 (1–2): 177–81. doi:10.1016/0166-4328(96)00092-7. PMID 8788498.