Article · Wikipedia archive · Last revised Jun 30, 2026

5-EAPB

5-EAPB, also known as 5-(2- propyl)benzofuran, is a potentially entactogenic amphetamine and benzofuran which is structurally related to 5-MAPB and 5-APB. It might be predicted to show similar effects to these drugs in humans, but the pharmacology of 5-EAPB remains unstudied as of 2020.

Last revised
Jun 30, 2026
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≈ 2 min
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Source
Wikipedia ↗
5-EAPB
Clinical data
Other names5-(2-(Ethylamino)propyl)benzofuran; 1-(Benzofuran-5-yl)-N-ethylpropan-2-amine
Routes of
administration		Oral
Drug classEntactogen
ATC code
  • None
Legal status
Legal status
Identifiers
  • 1-(1-benzofuran-5-yl)-N-ethylpropan-2-amine
CAS Number
PubChem CID
ChemSpider
UNII
CompTox Dashboard (EPA)
Chemical and physical data
FormulaC13H17NO
Molar mass203.285 g·mol−1
3D model (JSmol)
  • CC(NCC)CC1=CC(C=CO2)=C2C=C1
  • InChI=1S/C13H17NO/c1-3-14-10(2)8-11-4-5-13-12(9-11)6-7-15-13/h4-7,9-10,14H,3,8H2,1-2H3
  • Key:ZBZDDOARNPAMSP-UHFFFAOYSA-N

5-EAPB, also known as 5-(2-(ethylamino)propyl)benzofuran, is a potentially entactogenic amphetamine and benzofuran which is structurally related to 5-MAPB and 5-APB. It might be predicted to show similar effects to these drugs in humans, but the pharmacology of 5-EAPB remains unstudied as of 2020.

5-EAPB is similar in structure to compounds such as 5-APB which are claimed to be agonists of the 5-HT2C receptor2 as well as a triple monoamine reuptake inhibitor, however 5-EAPB is not listed as an example in this patent, and it is not yet established to what extent the activity of 5-EAPB resembles that of 5-APB.

Toxicity

Three people in their 30s were hospitalised after each taking approximately 500 mg of 5-EAPB, one of whom later died in hospital, whilst attending Brownstock music festival in Essex, UK on August 31, 2013.3

Interactions

Society and culture

Singapore

5-EAPB is listed in the Fifth Schedule of the Misuse of Drugs Act (MDA) and therefore illegal in Singapore as of May 2015.4

United Kingdom

In the UK, all benzofurans are considered Class B drugs5 and are therefore illegal.

See also

See also

References

References

  1. Anvisa (24 July 2023). "RDC Nº 804 - Listas de Substâncias Entorpecentes, Psicotrópicas, Precursoras e Outras sob Controle Especial" [Collegiate Board Resolution No. 804 - Lists of Narcotic, Psychotropic, Precursor, and Other Substances under Special Control] (in Brazilian Portuguese). Diário Oficial da União (published 25 July 2023). Archived from the original on 27 August 2023. Retrieved 27 August 2023.
  2. US patent 7045545, Briner K, Burkhart P, Burkholder P, Fisher MJ, Gritton WH, Kohlman DT, Liang SX, Miller SC, Mullaney JT, Xu YX, "Aminoalkylbenzofurans as serotonin (5-HT(2c)) agonists", published 19 January 2000, issued 2006-16-03, assigned to Eli Lilly and Co 
  3. Stretch E (1 September 2013). "Festivalgoer's death prompts drug warning". The Guardian.
  4. "CNB NEWS RELEASE". Central Narcotics Bureau (CNB). 30 April 2015. Archived from the original on 15 July 2015. Retrieved 24 July 2015.
  5. "Ban on NBOMe and benzofurans comes into force". Gov.uk. 10 June 2014.
External links