Article · Wikipedia archive · Last revised Jun 11, 2026

Α-Propyltryptamine

α-Propyltryptamine is a chemical compound of the tryptamine and α-alkyltryptamine families. It is the α-propyl derivative of tryptamine and is a higher homologue of α-methyltryptamine (AMT) and α-ethyltryptamine (AET). The compound was briefly mentioned by Alexander Shulgin in his 1997 book TiHKAL. He noted that it had been synthesized but that it had never been tested in humans to his knowledge. Moreover, he speculated that it would likely require a "pretty hefty dosage" for central effects based on extrapolation from the loss of potency with higher phenethylamine α-homologation like α-propylphenethylamines such as BDP (K).

Last revised
Jun 11, 2026
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≈ 1 min
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Wikipedia ↗
α-Propyltryptamine
Clinical data
Other namesAPT; αPT; α-PT; alpha-Propyltryptamine
ATC code
  • None
Identifiers
  • 1-(1H-indol-3-yl)pentan-2-amine
PubChem CID
ChemSpider
Chemical and physical data
FormulaC13H18N2
Molar mass202.301 g·mol−1
3D model (JSmol)
  • CCCC(CC1=CNC2=CC=CC=C21)N
  • InChI=1S/C13H18N2/c1-2-5-11(14)8-10-9-15-13-7-4-3-6-12(10)13/h3-4,6-7,9,11,15H,2,5,8,14H2,1H3
  • Key:OXTXKBQUVJLMPO-UHFFFAOYSA-N

α-Propyltryptamine (APT, αPT, or α-PT) is a chemical compound of the tryptamine and α-alkyltryptamine families.1 It is the α-propyl derivative of tryptamine and is a higher homologue of α-methyltryptamine (AMT) and α-ethyltryptamine (AET).1 The compound was briefly mentioned by Alexander Shulgin in his 1997 book TiHKAL (Tryptamines I Have Known and Loved).1 He noted that it had been synthesized but that it had never been tested in humans to his knowledge.1 Moreover, he speculated that it would likely require a "pretty hefty dosage" for central effects based on extrapolation from the loss of potency with higher phenethylamine α-homologation like α-propylphenethylamines such as BDP (K).1

See also

See also

References

References

  1. Shulgin AT, Shulgin A (September 1997). "α-Propyltryptamine". TiHKAL: The Continuation. Berkeley, California: Transform Press. ISBN 0-9630096-9-9. OCLC 38503252. Other homologues of α-ET have been synthesized. The α-propylhomologue (α-PT) has been made from tryptophan, and the acetate salt was recrystallized from ethyl acetate/MeOH and melted at 158–158.5 °C. It has not, to my knowledge, ever been tasted. But I suspect that it will take a pretty hefty dosage to get some CNS effect based on the loss of potency with the similar homologation in the Muni Metro series related to MDMA.
External links