Wermuth is a surname. Notable people with the surname include:
- Cédric Wermuth (born 1986), Swiss politician.
- Arthur W. Wermuth, a United States Army officer during World War II.
- Jochen Wermuth (born 1969), a German investor.
- Rut Wermuth (1928–2021), Polish Holocaust survivor.
- Nanny Wermuth (born 1943), professor emerita of Statistics.
- Camille G. Wermuth (died 2015), French chemist.