UBL5

UBL5
Available structures
PDB	Ortholog search: PDBe RCSB
List of PDB id codes
	1P0R, 4PYU
Identifiers
Aliases	UBL5, HUB1, ubiquitin like 5
External IDs	OMIM: 606849; MGI: 1913427; HomoloGene: 83305; GeneCards: UBL5; OMA:UBL5 - orthologs
Gene location (Human)
Chr.	Chromosome 19 (human)
End	9,830,115 bp
Gene location (Mouse)
Chr.	Chromosome 9 (mouse)
End	20,647,140 bp
RNA expression pattern
	Top expressed in
	anterior pituitary; ; right testis; ; left testis; ; right adrenal gland; ; mucosa of transverse colon; ; left adrenal cortex; ; right adrenal cortex; ; C1 segment; ; anterior cingulate cortex; ; monocyte;
	Top expressed in
	choroid plexus of fourth ventricle; ; interventricular septum; ; corneal stroma; ; ventricular zone; ; cardiac muscle tissue of left ventricle; ; yolk sac; ; lip; ; granulocyte; ; zygote; ; plantaris muscle;
	More reference expression data
	More reference expression data
Gene ontology
Molecular function	protein binding; protein tag;
Cellular component	cytoplasm; nucleus;
Biological process	mRNA splicing, via spliceosome; positive regulation of protein targeting to mitochondrion;
	Sources:Amigo / QuickGO
Orthologs
	59286
	66177
	ENSG00000198258
	ENSMUSG00000084786
	Q9BZL1
	Q9EPV8
	NM_024292; NM_001048241
	NM_025401; NM_001310746
	NP_001041706; NP_077268; NP_001041706.1; NP_077268.1
	NP_001297675; NP_079677; NP_001347954; NP_001347955; NP_001347956
	Wikidata
View/Edit Human	View/Edit Mouse

Ubiquitin-like protein 5 is a protein that in humans is encoded by the UBL5 gene.⁵

It has been shown that in C. elegans mitochondria treated to lower expression of certain electron transport chain proteins during the L3/L4 stage, its expression levels is higher leading to increased lifespans.⁶

Ubiquitin-like proteins (UBLs) are thought to be reversible modulators of protein function rather than protein degraders like ubiquitin (MIM 191339).[supplied by OMIM]⁵

References

GRCh38: Ensembl release 89: ENSG00000198258 – Ensembl, May 2017
GRCm38: Ensembl release 89: ENSMUSG00000084786 – Ensembl, May 2017
"Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
"Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
"Entrez Gene: UBL5 ubiquitin-like 5".
Mitochondrial Stress Signals Revise an Old Aging Theory - DOI 10.1016/j.cell.2010.12.023

External links

Overview of all the structural information available in the PDB for UniProt: Q9BZL1 (Human Ubiquitin-like protein 5) at the PDBe-KB.
Overview of all the structural information available in the PDB for UniProt: Q9EPV8 (Mouse Ubiquitin-like protein 5) at the PDBe-KB.

[refGRCh38Ensembl-1] GRCh38: Ensembl release 89: ENSG00000198258 – Ensembl, May 2017

[refGRCm38Ensembl-2] GRCm38: Ensembl release 89: ENSMUSG00000084786 – Ensembl, May 2017

[3] "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[4] "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[entrez-5] "Entrez Gene: UBL5 ubiquitin-like 5".

[6] Mitochondrial Stress Signals Revise an Old Aging Theory - DOI 10.1016/j.cell.2010.12.023

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References

Further reading

External links