Tomasulo is a surname. Notable people with the name include:
- Antonio Tomasulo (1917–1987), Italian-American mobster
- Dan Tomasulo (born 1951), American counseling psychologist, writer, and professor
- Frank P. Tomasulo, American film critic, theoretician, and historian
- Peter Tomasulo (born 1981), American professional golfer
- Robert Tomasulo (1934–2008), American computer scientist
- Tomasulo's algorithm, a computer architecture hardware algorithm for dynamic scheduling of instructions